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Subject: Calcineurin Departments: Department of Oncology Collections: Graduate and Postdoctoral Studies (GPS), Faculty of Collections: Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations

  • Nuclear Factor I and Calpain Signaling in Glioblastoma

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    Fall 2019

    Vo, Minh The

    Glioblastoma (GBM), classified as WHO grade IV astrocytoma, is the most common and lethal adult primary brain tumour. Despite recent advances in treatment, GBM prognosis remains largely unchanged with most patients succumbing to the disease within ~15 months of diagnosis. This dismal outcome can...

  • Nuclear Factor I in Malignant Glioma

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    Fall 2015

    Brun, Miranda

    Malignant glioma (MG), comprised of grade III (anaplastic astrocytoma) and grade IV (glioblastoma) astrocytoma, is the most common adult brain tumour, with an incidence of ~4 in 100 000 people. Despite aggressive treatment with surgery, radiation, and chemotherapy, survival remains dismal, with...

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