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- 1Beilman, Candace L
- 1El-Matary, Wael
- 1Eslamparast, Tannaz
- 1Gordon, Marilyn H
- 1Huang, Vivian Wai-Mei
- 1Klostermann, Natalie R
An Individualized and Multi-faceted Transition Intervention is Needed for Pediatric Patients with Inflammatory Bowel DiseaseDownload
The transition of chronically ill patients from pediatric to adult care can be challenging for patients and families and there is no gold standard for how to facilitate this process. An unsuccessful transition has been associated with more negative health outcomes. It is generally agreed upon by...
The aim of this work was to examine any possible IBD activity-related variations in immunoglobulin A (IgA) anti-tissue transglutaminase (tTG) levels in children with IBD. The prevalence of CD in children with IBD was also examined. In a prospective cohort study, children with IBD were screened...
Anti-TNF therapy is effective for the induction and maintenance of remission in patients with inflammatory bowel disease (IBD). The benefits of anti-TNF therapy include improved quality of life, steroid discontinuation, and reduced hospitalization and surgery rates. Due to their high costs and...
Background- Crohn's disease (CD) is a type of inflammatory bowel disease that can cause inflammation throughout the alimentary tract. Many individuals diagnosed with CD ultimately require intestinal resection. Unfortunately, disease often recurs following surgery. The pathophysiology of the...
Reproductive Knowledge Specific to Inflammatory Bowel Disease Among Women with IBD and Physicians who Treat Women with IBDDownload
BACKGROUND: Inflammatory Bowel Disease (IBD) affects women in their reproductive years. Women with IBD often choose not to have children, and this voluntary childlessness may be due to their concerns regarding the adverse effects of their IBD and its treatment on fertility, pregnancy, and the...
The Role of Vitamin D in Anti-Tumor Necrosis Factor-Alpha-Induced Response in Patients with Inflammatory Bowel DiseaseDownload
Vitamin D is an important immunomodulator of the immune system and has been suggested to play a role in the pathogenesis of inflammatory bowel disease (IBD). Drugs targeting TNF-alpha are effective IBD therapies, and vitamin D has been demonstrated to suppress TNF-alpha as well as work...
The tumor suppressor protein Ras association domain family 1A (RASSF1A) has roles in multiple signaling pathways including modulating apoptosis, the cell cycle, DNA damage, and microtubule organization. RASSF1A has been shown to be one of the most frequently epigenetically silenced genes in a...
The Validity of Patient-led Self- screens for Identifying Malnutrition in Inflammatory Bowel DiseaseDownload
Background: Malnutrition is common in Inflammatory Bowel Disease (IBD) and is associated with significant morbidity and mortality. Identification of high-risk patients using a sensitive and reliable screen is the first step to dietitian referral for nutritional assessment and intervention. Aim:...
The influence of iron therapy on the clinical outcomes, the colonic bacteria microbiome and the urinary metabolomics in iron deficient subjectsDownload
Iron deficiency is a common problem facing subjects with inflammatory bowel disease and it is of recurrent nature. It is associated with lethargy, fatigue and poorer cognition independent of anaemia. These symptoms could be reversed with iron supplementation either via oral or intravenous route....