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Roles for Transcription Factors and Signaling Pathways in Hindbrain Segmentation and Ventricle MorphogenesisDownload
During development, expression and localization of transcription factors and transcriptional co-regulators must be tightly controlled, and in turn they are required to regulate cellular identity and cellular processes. Often this involves complex interactions with signaling pathways. We are...
The roles of Pbx and Meis TALE-class homeodomain transcription factors in vertebrate neural patterningDownload
One of the major goals of developmental biology is to understand how specialized groups of cells arise from an initially unspecified cell population. The vertebrate hindbrain is transiently segmented along its anterior-posterior axis into lineage-restricted compartments called rhombomeres, making...