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Skip to Search Results- 1Adam, Ibrahim S. Y.
- 1Chow, Aaron K.Y.
- 1Gunda, Naga Siva Kumar
- 1Halpin, Anne M
- 1Haveroen, Melissa E
- 1Lak, Parnian
- 2Department of Agricultural, Food and Nutritional Science
- 2Department of Agricultural, Food, and Nutritional Science
- 2Department of Chemistry
- 1Department of Chemical and Materials Engineering
- 1Department of Mechanical Engineering
- 1Department of Medical Microbiology and Immunology
- 1Bressler, David (Agricultural, Food and Nutritional Science)
- 1Bressler, David (Department of Agricultural, Food and Nutritional Science)
- 1Gaenzle, Michael (Agricultural, Food and Nutritional Sciences)
- 1Gina R. Rayat (Surgery)
- 1Halloran, Philip (Medicine)
- 1Hidalgo, Luis (Laboratory Medicine & Pathology)
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A novel mouse model of acute antibody-mediated transplant rejection shows simultaneous complement activating and anti-inflammatory effects of donor specific IgG antibodies
DownloadFall 2013
We developed a small animal model of pure antibody-mediated rejection (ABMR) by utilizing fully major histocompatibility complex (MHC) mismatched kidney allografts in mice. By examining resultant ABMR pathology, we show that terminal complement products C5a and C5b-9 are crucial in establishing...
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Fall 2020
Introduction: ABO-incompatible organ transplants (ABOi-Tx) recipients are at high-risk of rapid rejection mediated by ABO antibodies (ABO Abs). To manage and expand ABOi-Tx, it is necessary to understand the mechanism(s) by which natural and induced ABO Abs develop. Prior studies have used...
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Fall 2014
Carbohydrate–protein interactions play key roles in a range of biological processes. Noticeable advancements have been made in understanding the features associated with the recognition of pyranosides (six-membered ring sugars) by proteins. In contrast, similar detailed studies about the...
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Spring 2010
Enterococcus faecalis 710C is a lactic acid bacterium that produces two bacterocins, ent7A and ent7B. Both ent7A and ent7B have strong activity against gram-positive food pathogens including Listeria spp., Clostridium spp., vancomycin-resistant enterococci (VRE) and methicillin-resistant...
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Spring 2014
The development of rapid detection techniques to be applied at the point of use, has been gaining significant attention in the recent years. Rapid techniques are important and preferable methods in healthcare and environment sector due to the advantages they offer such as low-cost and reduced...
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Effect of bacterial stress response on pathogen enumeration and its implications for food safety
DownloadSpring 2011
To determine the impact of stress response on enumeration, cell association status and the viability of Escherichia coli DH5α, Staphylococcus aureus ATCC 13565 and Listeria monocytogenes CDC 7762 were evaluated using fluorescence microscopy and were compared with the outcomes of traditional plate...
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Fall 2011
The mechanism of heat resistance in an exceptionally resistant strain of E. coli was investigated. E. coli AW1.7 was compared to a heat sensitive strain, E. coli GGG10. The heat resistance of both strains was increased by inclusion of NaCl, but only E. coli AW1.7 exhibited a consistent heat...
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Fall 2022
Background: Although pediatric heart transplantation is a life-saving and effective therapy for children with cardiac disease, barriers remain due to a lack of available organs as well as transplant failure due to rejection. This dissertation aimed to increase knowledge related to immune risk...
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Investigation on the uptake of functional proteins and infectious prions into wheat plants through the root system
DownloadSpring 2014
Prions are the proteinaceous particle responsible for infections in a class of neurodegenerative diseases. These diseases affect a number of mammals including cervids where it is termed Chronic Wasting Disease (CWD). Prions enter the environment and persist for years. Plants have the ability to...
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Fall 2009
Islet transplantation has the potential to be an effective treatment for patients with type 1 diabetes. However, a shortage of human donor islets and the need for continuous immunosuppressive therapy currently limit this therapy to patients with brittle type 1 diabetes. Neonatal pigs may...