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Children are often touted as being very important members of society because they represent our future. Optimizing their health outcomes has the potential for a huge impact on public health because children are at an early stage in the life trajectory. But it is often unclear how society...
Epilepsy is among the most common neurological diseases, but approximately 30% of epileptics are unresponsive to available drugs, and many more suffer significant side effects. One reason for the persisting large fraction of drug-resistant or drug-intolerant patients may be that most drug...
Temporal lobe epilepsy (TLE) and idiopathic generalized epilepsy (IGE) are two common epilepsy syndromes. TLE is a type of focal epilepsy. It is frequently associated with mesial temporal sclerosis (MTS), a condition that is also medically intractable. Although TLE is characterized by a focal...
Pharmacological and Fluorometric Assessment of Neuronal KCNQ Channels, and Implications for Understanding Neurological DiseaseDownload
Epilepsy affects 60 million people worldwide, and encompasses the most common forms of neurological disorders. Epilepsy manifests in diverse ways in patients, ranging from mild cognitive effects, to seizures, to the more severe epileptic encephalopathy. While many pharmacological approaches exist...
Approximately 50 million people worldwide suffer from epilepsy, a chronic neurological disorder characterized by recurrent seizures. While most patients with epilepsy will respond to anticonvulsant medications, approximately one third are found to have drug resistant epilepsy. Mesial temporal...