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- 2Electrospray Ionization
- 2Protein-Ligand Interactions
- 1Desorption Electrospray Ionization
- 1Enzyme Kinetics
Application of Electrospray Ionization Mass Spectrometry to Study Protein-Ligand Interactions and Enzyme KineticsDownload
This thesis describes the development and application of electrospray ionization mass spectrometry (ESI-MS) to study the noncovalent protein-ligand interactions and also investigate the kinetic of enzymatic reactions. The rate of glycolipids cleavage by the human neuraminidase 3 (hNEU3) was...
This thesis describes the development of mass spectrometry methods to study protein-ligand interactions in vitro. Liquid sample desorption electrospray ionization mass spectrometry (liquid sample DESI-MS) was first applied to quantify protein-carbohydrate interactions in aqueous ammonium acetate...