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Skip to Search Results- 3Cycloaddition
- 2Electrocyclization
- 1Allylic alcohol transposition
- 1Alternative Nazarov reaction
- 1Azides
- 1Bicyclization
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Spring 2010
A new method for the preparation of seven-membered carbocycles via cobalt-mediated [5+2] cycloaddition methodology is presented. We have demonstrated that CpCo(η5-pentadienyl)+ systems undergo cycloaddition reactions with alkynes in a diastereocontrolled and high-yielding process. When...
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Fall 2014
This dissertation expands the scope and understanding of the Nazarov electrocyclization and interception of the reactive cyclopentenyl cation intermediate that is formed though a 4π electrocyclization of a pentadienyl cation. An intermolecular process for interrupting the Nazarov is discussed....
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Fall 2014
The five-membered carbocycle is a structural motif found in a plethora of natural products and bioactive compounds. The Nazarov reaction has emerged as an effective method to synthesize cyclopentenones and acts as a tool for adding structural complexity to molecular frameworks. This dissertation...