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- 1Athecate hydroids
- 1Chronic obstructive pulmonary disease
- 1Diffusing membrane capacity
- 1Dopamine blockade
Characterizing the Mesolimbic Dopamine Reward Pathway in a Magel2-null Mouse, a Model of Prader-Willi SyndromeDownload
Prader-Willi Syndrome (PWS) is a genetic disorder characterized by extreme hyperphagia that can lead to severe obesity. The abnormal motivation to eat in PWS suggests a disruption in the hedonic feeding pathway, which is feeding based on reward as opposed to physiological need. Hedonic feeding is...
The computational ability of principal neurons and interneurons in the brain and their ability to work together in concert are thought to underlie higher order cognitive processes such as learning, memory, and attention. Dendrites play a very important role in neuronal information processing...
The Effect of Dopamine on Pulmonary Diffusing Capacity and Capillary Blood Volume Responses to ExerciseDownload
Pulmonary diffusing capacity increases during exercise to meet the increasing oxygen (O2) demand of the body. Expansion of pulmonary capillary blood volume (Vc) and diffusing membrane capacity (Dm) are important contributors to the increased diffusing capacity observed during upright cycle...
The purpose of this dissertation was to characterize the response of the pulmonary vasculature to exercise in health (including a pharmacological intervention) and in individuals with mild chronic obstructive lung disease. The first project studied the effect of a dopamine receptor blockade on...