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The exchange of native pathogens between wild and domesticated animals can lead to novel disease threats to wildlife. However, the dynamics of wild host-parasite systems exposed to a reservoir of domesticated hosts are not well understood. A simple mathematical model reveals that the spill-back...
An Adminstrative Data Merging Solution For Dealing With Missing Data In A Clinical Registry: Adaptation To ICD-9 to ICD-10Download
Background: We have previously described a method for dealing with missing data in a prospective cardiac registry initiative. The method involves merging registry data to corresponding ICD-9-CM administrative data to fill in missing data 'holes'. Here, we describe the process of translating our...
Human food production activities can dominate natural systems, altering ecological and evolutionary aspects of the environment. Disease-mediated interactions are of particular concern. For example, parasites may "spill-over'' from farms to wildlife. Parasites isolated on farms can evolve...
Forkhead (Fox) proteins are transcription factors that function in many processes including development, metabolism and cell cycle regulation. This gene family is divided into subfamilies that appear to originate from a common ancestor. I have identified the evolutionary selection pressures...
Identification of Hepatotropic Viruses from Plasma Using Deep Sequencing : A Next Generation Diagnostic ToolDownload
Jovel, Juan, Wong, Gane K., Mitchell, Troy , Rahbari, Mandana , Zhang, Yong , Mason, Andrew L., Jordan, Tracy, Law, John , Tian, Zhijian , Song, Deyong , O’keefe, Sandra , Carpenter, Eric, Patterson, Jordan , Wang, Weiwei, Meng, Bo , Wasilenko, Shawn T , Ford, Glenn
Identification of a putative quantitative trait nucleotide in guanylate binding protein 5 for host response to PRRS virus infectionDownload
Choi, I., Guan, L., Plastow, G. S., Liu, P., Koltes, J. E., Loyd, H., Boddicker, N. J., Eisley, C. J., Schroyen, M., Bao, H., Dekkers, J. C. M., Kommadath, A., Abrams, S. M., Reecy, J. M., Rowland, R. R. R., Serão, N. V. L., Lunney, J. K., Carpenter, S., Stothard, P., Fritz-Waters, E., Tuggle, C. K.
Background Previously, we identified a major quantitative trait locus (QTL) for host response to Porcine Respiratory and Reproductive Syndrome virus (PRRSV) infection in high linkage disequilibrium (LD) with SNP rs80800372 on Sus scrofa chromosome 4 (SSC4). Results Within this QTL,...
Imag(in)ing the cancerous body: representations of cancer in medical discourse and contemporary visual artDownload
This thesis examines representations of cancer in contemporary art, with a particular focus on unruly, un-idealized bodies at risk. In bringing together the discourses of art history and medicine, its aim is to engage conventions of visualizing cancer, and more importantly, to highlight the ways...
Landscape Ecology of Mule Deer (Odocoileus hemionus) and White-tailed Deer (O. virginianus) with Implications for Chronic Wasting DiseaseDownload
Chronic wasting disease (CWD) is a fatal prion disease of cervids that continues to spread into new regions of Canada despite containment efforts. I examine the importance of landscape connectivity using circuit theory and source/sink habitats that are based on selection, survival and...
Mapping of genomic regions associated with agronomic traits and resistance to diseases in Canadian spring wheatDownload
Wheat breeders, in addition to phenotypic selection, employ molecular markers in their programs for different purposes, including parental selection, quality control, analysis of advanced lines (cultivars), on genetic purity and identity, and for markers assisted selection. In the first study of...