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Development of Empirical Models to Predict Deposition of Aerosols in the Extrathoracic Airways of ChildrenDownload
The experimental studies described in this thesis were performed with the goal of measuring deposition of aerosols, inhaled either nasally or orally, in the extrathoracic airways of children in different age groups. We pursued in vitro methods and characterized the deposition of aerosols in the...
Study of Enhanced Deposition due to Magnetic Field Alignment of Ellipsoid Particles Using Direct Numerical SimulationsDownload
A recent in vitro study demonstrated a non invasive method to enhance local deposition in a small airway by controlling the angular position of magnetic high aspect ratio particles. This technique could mitigate the challenge of providing sufficient therapeutic effects when using aerosolized...
Most current models for the deposition of aerosol particles in the human lung are based on a Lagrangian reference frame, which is ill-suited for modeling transient eects. Deposition models based on an Eulerian reference frame are much better at capturing instantaneous time-dependent eects, though...