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- 1Alam, Kazi, MM
- 1Baleja, James D.
- 1Booker, Brandon K.
- 1Chehel Amirani, Morteza
- 1Dever, Brittany R
- 1Elliott, John Francis.
DNA-assisted Heterogeneous Integration of Micro- and Nanoelectronic Devices: Modeling, Control, and Rational Design of Selective AttachmentDownload
Heterogeneous integration is an electronic packaging approach that enables the fabrication and assembly of complete electronic subsystems from components fabricated with different substrates and processes. Current commercial techniques like robotic pick-and-place, fluidic self-assembly, and...
Benzo[a]pyrene diol epoxide (BPDE), a known carcinogen, is a reactive metabolite of benzo[a]pyrene (BP). BP is usually formed during combustion of organic substances, such as cigarette smoke, automobile emission exhaust, and industrial waste burning. BPDE can covalently bind to the nucleobases of...
Developing and Assessing an Environmental DNA Protocol for Detecting Amphibian Species in Lentic Systems in Alberta, CanadaDownload
Global declines of amphibian populations have resulted in increased interest in determining and monitoring the geographic ranges for both endangered and invasive amphibian species. Monitoring programs rely on detection techniques to amass data, techniques that must be dependable in order to...
Effective and adaptive conservation of a species requires knowledge of trend in abundance and distribution. Monitoring species that are highly mobile, cryptic, and occurring at low densities is especially challenging. This research investigates the local factors affecting the detectability of...
Molecular Dynamics Simulations of Polyethylenimine Mediated Nucleic Acid Complexation with Implications for Non-viral Gene DeliveryDownload
Gene therapy is a promising therapeutic technique that involves delivering nucleic acids into cells. Polycations have evolved into a major category of gene carriers. Polyethylenimine (PEI) is one of the most effective polycationic carriers. Furthermore, modifying PEI with certain lipophilic...
Hybrids formed by biological entities and human-made nano-structures have been intensively studied in recent years due to their very interesting properties and applications. DNA-carbon nanotube (CNT) hybrid is one such material and the motivation of this PhD study. The interaction of DNA building...
Electrons, the fundamental charge carriers in solid-state devices, possess three intrinsic properties: mass, charge and spin. Spin is a quantum mechanical property, but can be loosely visualized as a tiny “intrinsic” magnetic dipole moment attached to an electron. In conventional electron...
The assembly of nanoparticle building blocks into more complex nanostructures has important applications in analytical chemistry, materials science, medical science, optics, and electronics. Due to its exquisite specificity and programmable nature, DNA has emerged as a very promising biomolecule...
The Influence of Specific Ions and System Architecture on the Recognition and Reactivity of Two Charged Materials: DNA-Modified Gold Nanoparticle Aggregates and Planar SilicaDownload
DNA functionalized gold nanoparticles (GNP–DNA) offer simple colorimetric nucleic acid sensing with high selectivity and sensitivity. Consequently, they are promising in genetic profiling, disease diagnostics, and forensic applications. In the presence of a target nucleic acid, GNP–DNA forms...