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- 13Graduate Studies and Research, Faculty of
- 13Graduate Studies and Research, Faculty of/Theses and Dissertations
- 9Biological Sciences, Department of
- 9Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 3Chemistry, Department of
- 3Chemistry, Department of/Journal Articles (Chemistry)
The assembly of nanoparticle building blocks into more complex nanostructures has important applications in analytical chemistry, materials science, medical science, optics, and electronics. Due to its exquisite specificity and programmable nature, DNA has emerged as a very promising biomolecule...
The Influence of Specific Ions and System Architecture on the Recognition and Reactivity of Two Charged Materials: DNA-Modified Gold Nanoparticle Aggregates and Planar SilicaDownload
DNA functionalized gold nanoparticles (GNP–DNA) offer simple colorimetric nucleic acid sensing with high selectivity and sensitivity. Consequently, they are promising in genetic profiling, disease diagnostics, and forensic applications. In the presence of a target nucleic acid, GNP–DNA forms...
The isolation and characterization of two Stenotrophomonas maltophilia bacteriophages capable of cross-taxonomic order infectivityDownload
Background A rapid worldwide increase in the number of human infections caused by the extremely antibiotic resistant bacterium Stenotrophomonas maltophilia is prompting alarm. One potential treatment solution to the current antibiotic resistance dilemma is “phage therapy”, the clinical...
The mitochondrial genome of the hexactinellid sponge Aphrocallistes vastus: Evidence for programmed translational frameshiftingDownload
Background: Mitochondrial genomes (mtDNA) of numerous sponges have been sequenced as part of an ongoing effort to resolve the class-level phylogeny of the Porifera, as well as to place the various lower metazoan groups on the animal-kingdom tree. Most recently, the partial mtDNA of two glass...
Developing a simple, general, and isothermal self-replicating system is one of the key requirements for a simplified detection platform for nucleic acid sequences specific to a disease causing microrganism. One of the challenges in achieving nucleic-acid templated isothermal amplification is that...
Using Biomolecular Recognition to Selectively Self-Assemble Microscale Components onto Patterned SubstratesDownload
Modern nanofabrication technology in the 21st century has continued year after year to push the boundaries of what is possible at the nanoscale. With the advent of molecular electronics, single electron devices, nanoelectromechanical systems (NEMS), and other nanotechnologies, the near future...