SearchSkip to Search Results
Cyclin dependent kinase 1, Cdk1, inhibitory phosphorylation is at the core of conserved checkpoint mechanisms that prevent mitosis from interfering with DNA replication or repair. It is also crucial for coordinating cell cycle progression with morphogenetic processes during organismal...
Endocycles, which are characterised by repeated rounds of DNA replication without intervening mitosis, are involved in developmental processes associated with an increase in metabolic cell activity and are part of terminal differentiation. Endocycles are currently viewed as a restriction of the...