SearchSkip to Search Results
- 1Autoimmune disease
- 1Cytotoxic T-lymphocites
- 1Cytotoxic t lymphocytes
Cytotoxic T lymphocytes (CTL) play a critical role in immune surveillance and elimination of virus-infected and malignant cells. CTL utilize two major cell-contact dependent mechanisms to kill antigen-bearing target cells. One mechanism involves the directional release of cytolytic molecules...
Periodic solutions and bistability in a model for cytotoxic T-lymphocyte (CTL) response to human T-cell lymphotropic virus type I (HTLV-I)Download
HTLV-I is the first discovered human retrovirus and a causative agent of both adult T-cell leukemia (ATL) and HTLV-I-associated myelopathy (or tropical spastic paraparesis) (HAM/TSP). Previous models have been successful in providing insight into the progression of HTLV-I infection. The...