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Skip to Search Results- 1Forbrich, Alexander E
- 1Goldansaz, Seyed Ali
- 1Gushue, Danielle L
- 1Gyoba, Jennifer
- 1Kamtchum Tatuene, Joseph
- 1Kramer, David A
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Fall 2016
Antemortem identification of Creutzfeldt-Jakob disease (CJD) patients is initially based upon clinical presentation of the disease. Symptoms are assessed in combination with results from cerebrospinal fluid (CSF) analysis, electroencephalography (EEG), magnetic resonance imaging (MRI), and...
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Spring 2022
Carotid atherosclerosis is responsible for 15-25% of the nearly 8 million first-ever ischemic strokes that occur each year worldwide. This proportion has remained constant over the past three decades, thus suggesting that some patients with carotid atherosclerosis currently receive suboptimal...
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Correlation of Subregional Hippocampal Thickness Abnormalities with Positron Emission Tomography Phosphorylated Tau Measurements in Patients with Mild Cognitive Impairment and Alzheimer's Disease
DownloadFall 2023
Alzheimer’s disease (AD) is the most common cause of dementia and is an emerging public health crisis with 150 million cases projected globally by 2050. Biomarkers are playing an emerging role in AD research - however, existing biomarkers have substantial limitations. Magnetic Resonance Imaging...
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Evaluating the Role of Bacterial Lipopolysaccharide on Etiology and Pathogenesis of Transmissible Spongiform Encephalopathies
DownloadFall 2014
Transmissible spongiform encephalopathies (TSEs) or otherwise known as prion diseases are a class of fatal neurodegenerative diseases related to irreversible brain damage. Presently, there is no effective treatment or preventive strategy for this disease because the etiology and biological...
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Fall 2021
Background Human Immunodeficiency Virus (HIV) is a major cause of mortality and morbidity globally. Vertical transmission is the primary mode of HIV acquisition among infants. Although successful interventions have reduced vertical transmission to less than <2.9% in low-to-middle income countries...
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Identification of biomarkers associated with the onset and progression of ketosis in transition dairy cows
DownloadFall 2016
Ketosis is a common metabolic disorder of transition dairy cows during the early lactation period. Cows with ketosis have lower milk yield and reproductive performance, greater risk of other periparturient diseases, and higher culling rate. Although ketosis has been extensively studied, not many...
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Fall 2015
Despite considerable research progress towards characterizing the neurobiology of anxiety, the focus on putative behavioral markers and the absence of a common behavioural/neurobiological signature for the different classes of anxiolytic drugs have potentially slowed research into the neural...
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Spring 2018
The presence of natural oil seeps, abandoned well sites (generally containing light oil), and high quality source rocks along the coast of western Newfoundland has refocused interest on the region as an area for potential petroleum exploration and development. Most of the oil seeps and old well...
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Putative ante-mortem indicators of Alzheimer’s dementia: Analysis of fluid biomarker and neuroimaging studies
DownloadSpring 2019
Dementia is a clinical state, characterized by symptoms indicative of deterioration of memoryand cognitive functions that interferes with social or occupational functioning. According to2018 statistics, around 50 million people are living with dementia, and this number will increaseto 131.5...
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Quantitative Label-Free Comparative Proteomic Analyses of Eukaryotic Tissues via Mass Spectrometry
DownloadFall 2018
In recent years, rapid advances in genomic and transcriptomic sequencing technologies have enabled the compilation of vast libraries of protein sequences and thus an explosion in bioinformatics-based fields of research. Among these is proteomics – the study of global protein abundance within a...