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Skip to Search Results- 1Alrabeeah, Abdollah A. M.
- 1Causton, Norman D.
- 1Keelan, Monika.
- 1Kelly, Karen
- 1Kennelly, John
- 1Key, Jessie Adam
- 1Cairo, Christopher (Chemistry)
- 1Field, Catherine (AFNS)
- 1Hall, Dennis G (Chemistry Department)
- 1Jacobs, Rene (Agricultural, Food, and Nutritional Science)
- 1Jacobs, Rene (Department of Agricultural, Food, and Nutritional Science)
- 1Temelli, Feral (Agricultural, Food and Nutritional Science)
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Spring 2019
Phosphatidylcholine (PC), the most abundant phospholipid in eukaryotic cells, is an important component of cellular membranes and lipoprotein particles. The enzyme CTP: phosphocholine cytidylyltransferase (CT) regulates de novo PC synthesis in response to changes in membrane lipid composition in...
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Establishing the anti-cancer effects of unsaturated fatty acids and a novel oil on human breast cancer cells
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N-3 and n-6 fatty acids and conjugated linoleic (CLA) acid have been known to inhibit breast cancer cell growth, however, effects on normal cells and of single and mixtures of n-3 and n-6 pathway intermediates have not been thoroughly investigated. The objective of this thesis was to determine...
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Spring 2014
Mandatory folate fortification polices in North America have resulted in high levels of circulating folate in the population. At the same time, a trend toward increased energy intake and reduced energy expenditure has lead to an increased prevalence of obesity, characterized by an accumulation of...
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Fluorogenic and fluorescent bioorthogonal labelling strategies for examining glycoproteins and phospholipids
DownloadFall 2012
Traditional genetically-encoded imaging strategies are problematic for use in analysing cell surface interactions due to the heterogeneous nature of the cell surface, and the high level of post-translational modifications. Small molecule fluorophores can provide dynamic information on cell...
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Spring 2013
Egg yolk contains approximately 10% (w/w) phospholipids (PL), of which about 70% is phosphatidylcholine (PC). Conventional methods of PL extraction from egg yolk involve using hazardous organic solvents. Supercritical carbon dioxide (SC-CO2), as a "green" solvent, had been applied for the...
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Fall 2014
The study of target proteins in live cells is fundamentally important to understanding their molecular roles in biological processes. Applications of cell permeable small molecules in bioorthogonal reactions have been improved to selectively label proteins tag for the purpose of protein...