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Fall 2012

Campbell, Stephen J.

In response to genomic stress resulting from external and endogenous insults, the cell has acquired a set of complicated pathways that deal with the damage, which are collectively referred to as the DNA damage response (DDR). In order to repair double strand DNA breaks that may have occurred in...

Spring 2022

Kulepa, Ayodeji N

The DNA damage response (DDR) is critical for maintaining genomic integrity and prevention of genotoxic consequences leading to carcinogenesis. The DDR signaling cascade results either in the activation of the repair pathway, or initiation of apoptosis if the repair is not possible. Many...