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- 3Chakrabarti, Subhadeep
- 3Proctor, Spencer D.
- 3Steele, Michael A.
- 3Wu, Jianping
- 2Aguzzi, Adriano
- 74Graduate and Postdoctoral Studies (GPS), Faculty of
- 74Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 26Agricultural, Food and Nutritional Science, Department of
- 26Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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- 5Medical Sciences-Paediatrics
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- 2Bell, Rhonda (Agricultural, Food, and Nutritional Science)
- 2Jamali, Fakhreddin (Faculty of Pharmacy and Pharmaceutical Sciences)
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Maternal Iron and Vitamin D Status During and After Pregnancy and Their Relationships With Maternal and Child Health Outcomes: Evidence From the APrON Cohort Study
DownloadSpring 2023
Background: Investigations that assess how maternal iron or vitamin D status biomarkers change across pregnancy and postpartum, and their relationships with maternal and offspring outcomes, in cohorts of healthy pregnant individuals from high-income countries are limited. Recent reports suggest...
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Maternal long chain polyunsaturated fatty acid status during pregnancy and lactation in the APrON cohort.
DownloadFall 2013
INTRODUCTION: Docosahexaenoic (DHA) and arachidonic acid (AA) are long chain polyunsaturated fatty acids (LC-PUFA) that are essential for fetal and infant development. The overall aim of the study was to characterize DHA, EPA and AA status during pregnancy and lactation in the first cohort of the...
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Maternal Overweight Prior to Pregnancy and its Impact on the Infant Gut Microbiome and Subsequent Child Overweight Risk
DownloadSpring 2015
Background: Maternal overweight and obesity is a widespread problem in Canada that has been linked to many complications during pregnancy. The gut microbiome has been revealed to have origins during infancy, which might be influenced by maternal weight gain during pregnancy. It would be...
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Fall 2010
Human T-lymphotropic virus type I (HTLV-I) is a persistent human retrovirus characterized by life-long infection and risk of developing HAM/TSP, a progressive neurological and inflammatory disease. Despite extensive studies of HTLV-I, a complete understanding of the viral dynamics has been...
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Mechanisms of Neonatal Intestinal Failure-Associated Liver Disease: Exploring the Gut-Liver Axis
DownloadSpring 2018
Neonates with intestinal failure (IF), who must rely on parenteral nutrition (PN) for growth and maintenance of health, are at risk for intestinal failure-associated liver disease (IFALD). In neonates, short bowel syndrome (SBS) as a result of intestinal resection is the most common cause of IF....
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Method, degree and lineage of prenatal maternal stress: effects on inflammatory and stress marker profiles of reproductive tissues and pregnancy outcomes
DownloadSpring 2023
Lopes, Nayara Gabriela Antunes
Prenatal maternal stress (PNMS) is any type of stress that pregnant women and animals experience. It was reported that over 70% of pregnant women experience low to moderate stress, while 6% experience high stress. Growing evidence indicates that PNMS influences maternal and offspring health...
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Milk-derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) promote adipocyte differentiation and inhibit inflammation in 3T3-F442A cells
Download2015
Chakrabarti, Subhadeep, Wu, Jianping
Milk derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) have shown promise as anti-hypertensive agents due to their inhibitory effects on angiotensin converting enzyme (ACE). Due to the key inter-related roles of hypertension, chronic inflammation and insulin resistance in the...
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Spring 2020
The human neuraminidases (NEU1, NEU2, NEU3, and NEU4) are a family of enzymes implicated in pathologies including cancer and diabetes. Our group has developed selective inhibitors for these enzymes that have been employed as tools to understand their biological roles. Several reports have linked...
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Molecular imaging of cyclooxygenase-2 (COX-2) and autotaxin (ATX) in cancer using positron emission tomography (PET)
DownloadFall 2020
Positron emission tomography (PET) relies on the use of β+-emitting radionuclide-bearing molecules congregating and decaying at a specific site of interest. Use of these molecules, called radiotracers, which target common tumor characteristics has become a pillar in the diagnosis of cancer and...
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Fall 2016
Macrophages are the primary cells of innate immunity that provide the first line of defence against any external stimuli. Their phagocytic properties enable them to engulf invading microbes or foreign particles. The phagocytic capability of macrophages plays a major role in interfering with drug...