SearchSkip to Search Results
Eggs are an economical source of nutrient rich food containing essential nutrients but are also one of the eight most common foods causing allergy today. Eggs are present in a wide variety of foods including sauces, bread and pasta. A novel method for the production of hypoallergenic egg...
Pre and postnatal maternal distress and infant gut immunity in the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohortDownload
Introduction: Secretory immunoglobulin A (sIgA) plays a critical role in gut mucosal immunity and is a marker of immune maturation in early life. Delayed IgA production is associated with increased risk of allergic diseases. Animal models of stressful events before birth and during infancy show...
Respiratory Syncytial Virus infection biases the immune response in favor of Th2: the role of Indoleamine 2, 3-dioxygenaseDownload
Infants that develop severe bronchiolitis due to Respiratory Syncytial Virus (RSV) are at increased risk of developing asthma later in life. To begin my studies in vitro, purified RSV stock was needed. My first study established the critical steps in RSV purification to determine a procedure that...
CRTh2 (chemoattractant receptor-homologous molecule expressed on Th2 cells) is a marker for Th2 cells and activation through CRTh2 stimulates expression of cytokines that are important for allergic responses such as IL-4, IL-5 and IL-13. We have observed CRTh2+ T cells express the IL-25 receptor...
Epidemiological studies correlate vitamin D deficiency with asthma severity. Calcitriol modulates receptor and cytokine expression from various leukocytes in an anti-inflammatory manner. Despite eosinophil activity during mucosal inflammation, knowledge on the direct effect of calcitriol on this...