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Skip to Search Results- 1Djkowich, Mikelle J
- 1Elyasi, Maryam
- 1Heyd, Amber T
- 1Hobson, N.
- 1Lefebvre, Megan, Elizabeth
- 1Martin, Leah J.
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Cost - effectiveness of integrating methadone maintenance with antiretroviral treatment in injection-driven HIV epidemics
DownloadSpring 2012
In the household survey, Health-Related Quality of Life (HRQL) of patients on antiretroviral treatment (ART) was profoundly reduced and significantly lower among drug users (DUs) than that of non-DUs, especially in the psychological and social dimensions. Drug use is known to negatively affect...
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Developing and Testing a Theoretical Model to Determine Children’s Adherence to Oral Health Behaviours
DownloadFall 2020
Background: Adherence to health care advice is a complex health concern especially when it involves children. Dental caries has been identified as the most common chronic childhood disease that occurs in a continuum. At the same time, it can be prevented by adherence to proper oral health...
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Exploring the Relationship Between Depression and Adherence in Individuals with Type 2 Diabetes
DownloadFall 2020
Background: Depression is a well-known risk factor for poor medication adherence in individuals with diabetes; however, this association is based on cross-sectional and cohort studies measuring adherence after depression is diagnosed. Symptoms of depression often progress before medical...
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Generation of a restriction minus enteropathogenic Escherichia coli E2348/69 strain that is efficiently transformed with large, low copy plasmids
Download2008
Raivio, T.L., Price, N.L., Ward, J.D., Hobson, N.
Background Many microbes possess restriction-modification systems that protect them from parasitic DNA molecules. Unfortunately, the presence of a restriction-modification system in a given microbe also hampers genetic analysis. Although plasmids can be successfully conjugated into the...
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Management of Latent Tuberculosis Infection Among an Inner-city Population with Psychosocial Barriers to Treatment Adherence
DownloadFall 2020
BACKGROUND: In Canada, preventive therapy for LTBI has meant long durations and frequent dosing. This contributes to poor adherence and completion rates. In response, a shortened treatment regimen, once weekly rifapentine plus isoniazid for 3 months (3HP), is now available, though there has been...
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Fall 2016
Background: A pilot community-based antiretroviral therapy (CBART) program in western Uganda was previously shown to significantly improve quality of life outcomes among HIV patients in their first year of treatment, though certain psychosocial challenges and issues remained. What is not known...
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Outcomes of antiretroviral therapy in northern Alberta: the impact of Aboriginal ethnicity and injection drug use
DownloadFall 2009
Background: Aboriginals are overrepresented in Canada’s HIV epidemic and are more likely to be infected with HIV through injection drug use (IDU) than non-Aboriginals. However, little research has investigated the outcomes of combination antiretroviral therapy (cART) among Aboriginal...
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Refocusing the focus on adherence to antiretroviral therapy using a community-based participatory research approach
DownloadFall 2014
Adherence to antiretroviral therapy is critical to treatment success. Using an epidemiological and community-based participatory research approach, my thesis reports on two papers related to antiretroviral therapy success (and subsequent failure). My thesis also includes a third paper which...
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Who is Using Non-Invasive Ventilation? A Descriptive Study Examining the Population Enrolled in a Pediatric Non-Invasive Ventilation Program
DownloadSpring 2020
The use of non-invasive ventilation (NIV) in infants and children is increasing. This thesis examined the population of infants and children enrolled in a quaternary pediatric hospital’s NIV program with the goal of describing the clinical characteristics of that population over a one-year...