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- 2Physical Education and Recreation
- 1Centre for Neuroscience
- 1Department of Biological Sciences
- 1Department of Chemistry
- 1Department of Computing Science
- 2Jones, Kelvin (Physical Education and Recreation)
- 1Allison, W. Ted (Biological Sciences)
- 1Berry, Tanya (Physical Education and Recreation)
- 1Bubela, Tania (School of Public Health)
- 1Collins, David (Physical Education and Recreation)
- 1Dal Bello-Haas, Vanina (School of Rehabilitation Science McMaster University)
Acid Labile Surfactants Containing Ketal-Linkage in Micellar Electrokinetic Chromatography and Electrospray Ionization Mass SpectrometryDownload
The combination of micellar electrokinetic chromatography (MEKC) with electrospray ionization mass spectrometry (ESI-MS) would yield a very powerful analytical technique. However, hyphenating both techniques is not easy. Sodium 4-[(2-methyl-2-undecyl-1,3-dioxolan-4-yl) methoxy]-1-propane...
Axon excitability testing shows increased IH activity in populations of slow versus fast motor axons of the ratDownload
Despite extensive knowledge of variations in motoneuron (MN) soma and muscle properties across different healthy muscles or motor units, there is comparatively little knowledge about variations in motor axon electrophysiology across different axon groups. Axon excitability testing (AET) is an in...
The pre and post diagnostic phases of amyotrophic lateral sclerosis (ALS) care are inherently uncertain for patients and caregivers. The emotional character of ALS related communications requires that providers have a high degree of skill and tact. Understanding patient and caregiver preferences...
Amyotrophic lateral sclerosis (ALS) is a highly heterogeneous disease in terms of its clinical presentation, progression, and detected pathology in the body. It is a multi-system degenerative disorder, though a diagnosis is made based on the presence of both upper motor neuron (UMN) and lower...
Intentions of Canadian healthcare professionals to prescribe exercise to people with amyotrophic lateral sclerosisDownload
Lack of effective treatment options exist for individuals with amyotrophic lateral sclerosis (ALS). A relatively inexpensive treatment option for people with ALS (PALS) is exercise. However, it is unclear whether healthcare professionals (HCP’s), working in ALS clinics across Canada, currently...
Regulatory factors gdf6a, tbx2b, and thr beta in generation of multiple cone photoreceptor subtypes; and intersections of genetic factors SOD1, TDP43, and gdf6a in zebrafish models of amyotrophic lateral sclerosisDownload
The work within this thesis may be divided into two major foci with a unifying theme of understanding neurodegeneration and expanding the foundational knowledge necessary for treatment of two major degenerative diseases: macular degeneration and amyotrophic lateral sclerosis. To these ends the...
Image texture is defined as visual patterns appearing in images. The powerful perceptive capability of texture features has made texture analysis a major research topic in computer vision and image processing. Texture features are used to detect defective products in factories, to understand...
The effects of a volitional breathing technique on swallowing and respiratory coordination in individuals with Amyotrophic Lateral Sclerosis: A procedural ProtocolDownload
Amyotrophic lateral sclerosis (ALS), commonly referred to as Lou Gehrig’s disease, is a common motor neuron disorder resulting in the deterioration, weakness and eventual atrophy of many of the key muscles of the body required to sustain life. Breathing and swallowing problems are common among...
The effects of a volitional breathing technique on swallowing and respiratory coordination in individuals with amyotrophic lateral sclerosis (ALS)Download
Introduction: Breathing and swallowing are integrally related biomechanical processes that are often impaired in people with ALS (PALS). This may lead to significant functional impairments that negatively impact their quality of life. Purpose: The purpose of the overall project was to...