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- 2Gänzle, Michael G.
- 2Valcheva, Rosica
- 1Baracos, Vickie
- 1Dieleman, Levinus
- 1Dieleman, Levinus A.
- 1Farhangfar, Arazm
Chemically defined diet alters the protective properties of fructo-oligosaccharides and isomalto-oligosaccharides in HLA-B27 transgenic ratsDownload
Non-digestible oligosaccharides (NDO) were shown to reduce inflammation in experimental colitis, but it remains unclear whether microbiota changes mediate their colitis-modulating effects. This study assessed intestinal microbiota and intestinal inflammation after feeding chemically defined...
The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in ratsDownload
CPT-11 is a drug used as chemotherapy for colorectal cancer. CPT-11 causes toxic side-effects in patients. CPT-11 toxicity has been attributed to the activity of intestinal microbiota, however, intestinal microbiota may also have protective effects in CP!-11 chemotherapy. This study aimed to...