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Study of Non-Covalent Protein-Carbohydrate Interactions using Electrospray Ionization Mass SpectrometryDownload
This thesis describes the development and application of electrospray ionization mass spectrometry (ESI-MS) methods to study protein-carbohydrate interactions in vitro. The affinities (Ka) of two recombinant fragments of Clostridium difficile toxins (TcdA & TcdB) and a library of the most...