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Tumor necrosis factor triggers the expression and activation of matrix metalloproteinases through NADPH-dependent superoxide productionDownload
Tumor necrosis factor (TNF) is upregulated in a number of cardiomyopathies. This thesis investigates TNF in triggering the expression and activation of matrix metalloproteinases (MMPs) in pressure overload cardiac disease, and explores the role of superoxide. Cardiac pressure overload was...