Search
Skip to Search Results- 2Herzog, Jens A
- 2Miyashita, Tetsuto
- 2Richardson, Evan Shaun
- 2Vernygora, Oksana V
- 1Abbott, Sean P. (Sean Patrick), 1966-
- 1Abd Elhafiz, Areeg
Results for "departments_tesim:"Department of Biological Sciences""
-
Transcriptional Regulation of Gene Expression at Early Stages of Arabidopsis Vein Development
DownloadFall 2016
How multicellular organisms activate gene expression in the correct cells at the correct time is a central question in biology. In animals, in which this question has been investigated extensively, broadly expressed transcription factors activate target gene expression in narrow domains by a...
-
Transcriptional regulation of the zebrafish activation-induced cytidine deaminase (AID) gene
DownloadFall 2012
Activation-induced cytidine deaminase (AID, encoded by Aicda) mediates affinity maturation of immunoglobulin genes. Early studies in mammals indicated that the transcription of Aicda was regulated by a number of transcriptional regulatory regions, including a B-cell specific enhancer in the...
-
Transcriptional regulation of two immune genes: teleost activation-induced cytidine deaminase and duck major histocompatibility complex class I
DownloadFall 2015
Differential gene expression allows organisms to develop specialized cell types and promptly respond to foreign pathogens. I) Activation-induced cytidine deaminase (AID/Aicda) is expressed in B-cells to diversify the secondary repertoire and effector functions of antibodies during the processes...
-
Spring 2013
The plant vascular system is a network of vascular strands that transport nutrients and signals. Some of these signals control the development of non-vascular tissues surrounding vascular strands; some others coordinate the development of new branches, leaves, and flowers with that of new roots....
-
Transcriptome and Proteome Based Survey to Identify Aluminum-Responsive Genes in Roots of Arabidopsis Thaliana
DownloadSpring 2010
Aluminum (Al)stress is a major limitation to crop productivity on acidic soils. To help understand the cellular mechanisms underlying the toxicity and resistance of plants to Al, this thesis involved a large-scale, transcriptomic and proteomic analysis of roots of Arabidopsis thaliana and reports...
-
Transcriptomic analyses of Pinus contorta responses to Grosmannia clavigera under contrasting levels of nitrogen availability
DownloadSpring 2021
In western Canada alone, the current mountain pine beetle (MPB) outbreak has devastated nearly 19 million hectares of pine forest, negatively impacting communities, industries and ecosystems. Reforestation efforts can benefit from a deeper understanding of the impact of nitrogen (N)-based...
-
Transcriptomic analysis of zebrafish prion protein mutants supports conserved cross-species function of the cellular prion protein; and zebrafish as a model for cisplatin induced ototoxicity and transition metals as potential ligands for Tlr4ba and Tlr4bb
DownloadFall 2021
The work presented in this thesis is split between two projects. The first utilises prp1 and prp2 knockout zebrafish to investigate physiological functions of the cellular prion protein (PrPC). The second builds upon the use of zebrafish as a model for hearing loss to confirm a role of toll-like...
-
Fall 2016
Transferrin is an evolutionary conserved protein that in addition to having a critical role in iron transport also has been shown to have a crucial role in host defence. Transferrin has been shown to sequester iron from invading pathogens, act directly against microbial pathogens, and is an...