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2023-01-30

Thomas Hillen, Alexandra Shyntar

Cancer stem cells (CSCs) are pluripotent cancer cells, which are less sensitive to treatments, and which can generate new tumors once transplanted into a healthy tissue environment. They have been identified in many cancers and they are the driving force of cancer growth and metastasis....

2021-01-01

Pouria Ramazi, Mélodie Kunegel-Lion, Russell Greiner, Mark A. Lewis

2020-01-14

Peter D. Harrington, Mark A. Lewis

In marine systems, adult populations confined to isolated habitat patches can be connected by larval dispersal. Source–sink theory provides effective tools to quantify the effect of specific habitat patches on the dynamics of connected populations. In this paper, we construct the next-generation...

2020-01-19

Mélodie Kunegel-Lion, Mark A. Lewis

The efficacy of direct control methods in bark beetle outbreaks is a disputed topic. While some studies report that control reduces tree mortality, others see little effect. Existing models, linking control rate to beetle population dynamics and tree infestations, give insights, but there is a...

2020-01-14

Nathan G. Marculis, Mark A. Lewis

The method of inside dynamics provides a theory that can track the dynamics of neutral gene fractions in spreading populations. However, the role of mutations has so far been absent in the study of the gene flow of neutral fractions via inside dynamics. Using integrodifference equations, we...

2020-02-01

Melodie Kunegel-Lion, Rory L. McIntosh, Mark A. Lewis

The data presented in this article are related to the research article entitled “Mountain pine beetle outbreak duration and pine mortality depend on direct control effort” [1]. This article provides presence of mountain pine beetle infested trees detected by the Saskatchewan Forest Service on a...

2020-01-01

Stephanie J. Peacock, Martin Krkošek, Andrew W. Bateman, Mark A. Lewis

Parasite transmission between farmed and wild salmon affects the sustainability of salmon aquaculture in Pacific Canada. Understanding and managing parasites in aquaculture is challenged by spatial and temporal variation in transmission dynamics. We developed a mechanistic model that connects sea...

2020-07-31

Dean Koch, Subhash Lele, Mark A. Lewis

When working with contemporary spatial ecological datasets, statistical modellers are often confronted by two major challenges: (I) the need for covariance models with the flexibility to accomodate directional patterns of anisotropy; and (II) the computational effort demanded by high-dimensional...

2020-01-01

S. M. Fischer, M. Beck, L.-M. Herborg, M. A. Lewis

Human traffic along roads can be a major vector for infectious diseases and invasive species. Though most road traffic is local, a small number of long-distance trips can suffice to move an invasion or disease front forward. Therefore, understanding how many agents travel over long distances and...

2020-05-19

Stephanie J. Peacock, Martin Krkošek, Mark A. Lewis, Péter K. Molnár

Migrations allow animals to track seasonal changes in resources, find mates, and avoid harsh climates, but these regular, longdistance movements also have implications for parasite dynamics and animal health. Migratory animals have been dubbed “superspreaders” of infection, but migration can also...