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Studying Systemic Metabolic Remodeling and Abnormal Mitochondrial Signaling in Primary Biliary Cholangitis
DownloadFall 2024
Primary biliary cholangitis (PBC) is linked with the production of anti-mitochondrial antibodies (AMA) targeting pyruvate dehydrogenase complex-E2 subunit (PDC-E2). Cholangiocytes from PBC patients express increased PDC-E2, which is thought to result in loss of tolerance to mitochondrial...
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Fall 2024
This thesis analyzes surrogacy regulation and practice in Canada and India and examines how both altruistic and commercial surrogacy have the potential to harm and exploit surrogates. I argue that money might not be the sole reason (or even the main reason) for the potential for harm and...
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Exploring Sikh Punjabi Canadian Women’s Experiences of Navigating Salient Familial and Cultural Expectations
DownloadFall 2024
Several South Asian women in Western contexts navigate significantly challenging gendered expectations from their families and cultural communities pertaining to academics, career (Baggulay & Hussain, 2014), domestic responsibilities (Mustafa et al., 2020), family management, cultural...
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The Linguistics of the Environment: A Corpus-based Study of German Precipitation Constructions
DownloadFall 2024
This dissertation provides a corpus-based constructional analysis of precipitation events in German (e.g., es regnet ‘it rains’) based on real-world data from Sketch Engine’s deTenTen13 16.5 billion-word web corpus. The research was sparked by a large, cross-linguistic survey of weather event...
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Fall 2024
In this thesis, we investigate the problem of robustness and resilience in simultaneous localization and mapping systems (SLAM). With the vast adoption of robotics in many industries and disciplines, robustness and resilience are becoming of immense importance for the reliable and safe deployment...
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Longitudinal Monitoring of Physiological, Psychological and Molecular Responses to Different Dietary Interventions: A Precision Health Approach
DownloadFall 2024
Diet and lifestyle choices are critical in shaping overall health, especially as chronic diseases become more widespread. With growing recognition of individual differences in responses to dietary interventions, personalized healthcare approaches are gaining importance. Precision nutrition (PN)...
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Fall 2024
Through qualitative in-depth interviewing and inductive thematic analysis, this research seeks to amplify the experiences of a population in Library and Information Studies (LIS) that is often underrepresented: Black, Indigenous and People of Colour (BIPOC) who are in the Master of Library and...
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Revisiting reclaimed well pads in boreal forests: the role of time and changing criteria in the recovery of vegetation composition, forest structure, and plant traits
DownloadFall 2024
Boreal forests provide multiple ecological and economic services, including carbon storage, provision of wildlife habitat and recreational space, and timber supply. In Canada’s western boreal forests, natural resource energy exploration and extraction results in substantial anthropogenic...
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Effects of the Menstrual Cycle on Daily Blood Glucose Changes During Exercise and in Recovery in Aerobically Fit Athletes
DownloadFall 2024
Background: Glucose monitoring is becoming increasingly popular in athletes who are hoping to optimize their nutrition, training and recovery. Glucose regulation is influenced by several factors, including the amount and type of exercise performed as well as circulating ovarian hormones in female...
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Fall 2024
Protein adsorption to implanted biomaterials can direct host responses and lead to health complications and device failure. Polyethylene oxide (PEO) is the gold standard film for reducing non-specific protein adsorption. Although polymer chain density is an important factor in determining PEO’s...