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Characterization of Galectin-9+ and TIGIT+ Natural Killer Cells in Human Immunodeficiency Virus-1 Infected Individuals
DownloadFall 2019
NK cells play an integral role in mediating immune responses to viral infections; however, their function is compromised during chronic diseases such as HIV-1, partly due to an increase in expression of inhibitory receptors. Thus, one of the reasons for the reduced immune responses elicited by NK...
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Cesarean Section and other Birth Interventions: impact on Clostridioides difficile (C. difficile) colonization in the infant gut microbiota in the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort
DownloadSpring 2019
Abstract Background Medical interventions during childbirth are increasing, with cesarean section (CS) delivery exceeding recommended rates by 13-15 % in Canada. CS has been associated with gut dysbiosis in early life. Infants who bypass this beneficial maternal bacterial inoculation during...
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Fall 2018
Colchicine is an anti-mitotic drug that targets unpolymerized tubulin, and inhibits microtubule polymerization. It is primarily used to treat gout but has been investigated in numerous clinical trials to treat conditions such as leukemia (ALL), prostate cancer, and inflammatory diseases. However,...
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Atomic Layer Deposition of Metal Oxides for the Preparation of High Performance Zn-Air Battery Electrodes
DownloadSpring 2020
As the world continues to implement renewable energy technologies such as wind and solar, comes the demand for grid scale energy storage. Zn-air batteries (ZABs) are a promising candidate for grid scale energy storage because of their high energy density, low cost, high safety, and low...
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Art, Activism and the Creation of Awareness of Missing and Murdered Indigenous Women and Girls (MMIWG); Walking With Our Sisters, REDress Project
DownloadSpring 2020
Artistic expression can be used as a tool to promote activism, to educate and to provide healing opportunities for the families of missing and murdered Indigenous women and girls (MMIWG). Indigenous activism has played a significant role in raising awareness of the MMIWG issue in Canada, through...
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Above, Beneath, and Within: Collaborative and Community-Driven Archaeological Remote Sensing Research in Canada
DownloadSpring 2020
This thesis investigates the application of geophysics and remote sensing techniques in community-driven and collaborative archaeology research in Canada. While these techniques have become common among some archaeologists, they have yet to be extensively used within the lens of Indigenous...
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A Focused Ethnography of Indigenous Women Accessing Healthcare Services in Northern and Rural Thailand
DownloadFall 2018
There is far ranging evidence indicating that access to healthcare services is not equitable in Thailand, particularly among disadvantaged populations like Indigenous women. What has yet to be explored is Indigenous women’s access to, and experiences of, the Thai healthcare system. In particular,...
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Fall 2019
As children are now growing up with and around computers and digital technologies, their experiences using these technologies differ from their parents’. This study examines how young Somali children and their parents experience using technology and computers, while seeking to understand...
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Spring 2019
Over the last few decades the incidence of obesity has increased remarkably in Canada and in the rest of the world, with the highest increases occurring in the excessive weight categories class II (BMI 35– 39.9) and class III (BMI ≥ 40). By 2019, it is anticipated that over 20% of the Canadian...
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Analyzing Network Connectivity by Cyclist Comfort: An Empirical Reappraisal of the Four Types of Cyclists Typology and Level of Traffic Stress Framework
DownloadFall 2019
North America is seeing a resurgence of interest in cycling both for recreation and as a transportation mode. Cycling is touted as a means to reduce traffic congestion and its GHG emissions and pollution, increase livability, and provide a remedy to inactivity and its related health problems....