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Mast Cell Response to Influenza A Infection and Their Antiviral Activity in Co-culture with Epithelial CellsDownload
Well known their role in allergic inflammation, mast cells (MC) are also important in innate immunity against pathogens. MC are abundant in the respiratory tract and in close proximity to epithelial cells (EC) where they could be important in host defenses or the pathogenesis of viral infections...
Nitric oxide (NO) is a short-lived free radical that plays a critical role in the regulation of cellular signalling. Mast cell (MC) derived NO and exogenous NO regulate MC activities including the inhibition of MC degranulation. At a molecular level the intermediate metabolites of NO modify...
Mast cells are immune cells important in innate immunity. Besides their role in asthma and allergies, mast cells are critical effector cells against various pathogens. Mast cells are established to be protective against bacterial infections, but little is known about their functions in viral...