Search
Skip to Search Results-
Effects of Genetic Deletion of Soluble Epoxide Hydrolase on Cardiac Function and Inflammation in Acute Lipopolysaccharide Injury
DownloadSpring 2022
Acute inflammatory syndromes, such as endotoxemia, elicit detrimental multi-organ responses resulting in cardiac dysfunction often leading to death. Emerging evidence suggests epoxylipids can exert cardioprotective effects by modulating the NOD-like receptor family pyrin domain containing 3...
-
Spring 2022
Radioisotopes of scandium have been proposed as potential candidates for radiotheranostics, the combination of targeted imaging and therapy of cancer. Radiolabelling specific targeting vectors with positron emitting radioisotopes (43Sc, 44Sc) provides a quantitative measure of the disease through...
-
Water-mediated adhesion of oil sands on solid surfaces at low temperature and possible solutions to mitigate adhesion
DownloadSpring 2022
Adhesion of frozen granular materials on solid surfaces creates various problems for surface cleaning, reduces the carrying capacity of vehicles, and increases energy consumption for inland transportation. Here in the first part of this thesis, water content demonstrates to determine the adhesion...
-
Spring 2022
This study investigated the mechanisms driving the dewatering and strength behaviour of polymer amended treated (centrifuged and in-line thickened tailings/ILTT) deep tailings deposits undergoing seasonal weathering dominated by a) multiple freeze-thaw cycles and b) alternating freeze-thaw and...
-
Opioid Prescribing Patterns for Treatment of Acute and Chronic Pain in Rural and Urban British Columbia
DownloadSpring 2022
Throughout Canada there has been an increase in both fatal and non-fatal opioid related overdoses, with British Columbia having some of the highest rates. In response to this increase, the Provincial Health Officer of British Columbia declared a public health emergency to mobilize resources to...
-
Spring 2022
Radiology reports are the primary medium through which physicians communicate findings and diagnoses from patients' medical scans. Examples include radiology reports for chest radiographs, CT scans of the brain, medical reports of retinal images, and more. However, the process of writing medical...
-
Spring 2022
Primary herpes simplex virus 1 (HSV-1) infections are common in childhood, affecting mainly the oropharyngeal mucosa. The virus is then transported to the neuronal bodies in the trigeminal ganglia, where it establishes lifelong latency. Although latent infections are asymptomatic, HSV-1...
-
Reflected Backward Stochastic Differential Equations for Informational Systems with Applications
DownloadSpring 2022
The core innovation of this thesis lies in studying reflected backward stochastic differential equations (RBSDE hereafter) for informational systems. An informational system is a system where there is discrepancy in the information received by agents over time. In this thesis, we restrict to the...
-
Development and use of a ray-based analysis tool for the investigation of stimulated Raman scattering in laser-plasma interaction experiments
DownloadSpring 2022
Recent long-scale-length spherical target experiments, performed on the OMEGA EP laser, are analyzed for stimulated Raman side-scattering (SRSS). This work has been motivated by results obtained on experiments performed at the Nation Ignition Facility (NIF), relevant to directly-driven inertial...
-
Radiobiological Modeling and Experimental Quantification of Radiobiological Parameters used in Cervical Cancer Brachytherapy Dose Calculation
DownloadSpring 2022
Cervical cancer is the fourth most common cancer worldwide, with an estimated 604,000 cases identified in 2020. The standard care for locally advanced cervical cancers is concurrent chemotherapy and external beam radiotherapy (EBRT) with a brachytherapy (BT) boost. Current guidelines recommend...