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Spring 2020

Abu Fadaleh, Sarah

Medication appropriateness is a fundamental target for the healthcare system, particularly in relation to older adults. Because polypharmacy and multimorbidity are prevalent in older adults, they are more prone to the risks of having an inappropriate medication. They are also more prone to...

Spring 2020

Woit, Cassandra

In 2007, Additional Prescribing Authorization (APA) was introduced in Alberta, which allows pharmacists to independently initiate prescriptions and prescribe to manage ongoing therapy. Pharmacist prescribing has also been shown to have positive patient outcomes in a variety of health conditions....

Spring 2020

Moura Paiva, Igor

Active targeting strategies have been pursued to improve the efficacy and safety of cancer therapeutics and theranostics. The significant benefit of tumor homing ligands conjugated to small molecules versus nanoparticle delivery systems in enhancing drug delivery to the tumor is still a matter of...

Fall 2020

Niaz, Diva

Background: Depression is a well-known risk factor for poor medication adherence in individuals with diabetes; however, this association is based on cross-sectional and cohort studies measuring adherence after depression is diagnosed. Symptoms of depression often progress before medical...

Fall 2020

Jamieson, Kristi Lockhart

Ischemic heart disease (IHD) is a significant cause of morbidity and mortality for Canadians. While mortality rates from myocardial infarction (MI) and heart failure (HF) have decreased, IHD remains the number one cause of premature mortality. Both age and sex are important contributors for IHD...

Fall 2020

Idowu, Omowumi O.

Pharmacists could have an important role to play in reducing the increasing societal burden of Chronic Obstructive Pulmonary Disease through the professional services they provide. The overall objective of this thesis is to contribute to a multi-phased research aimed at developing an intervention...

Fall 2020

Wajda, Benjamin

In an effort to address shortcomings with current drug treatments for osteoporosis (OP) and improve the efficacy of human parathyroid hormone (hPTH(1-34)), we have employed a bisphosphonate-conjugation strategy by tethering hPTH(1-34) to a non-nitrogenated bisphosphonate (BP) moiety (BP-PTH) in...

Spring 2019

Abdulsalam Alharbi

One of the major limitations of chemotherapy in cancer treatment is the side effects of anti-cancer drugs. This happens due to non-selective distribution of most standard chemotherapies, and their action on cancer and all normal dividing cells. The objective of this project is to develop a novel...

Spring 2019

Siyam, Tasneem

Background: Early surgical menopause results in severe and prolonged health consequences due to early estrogen deprivation. Hormone therapy (HT) is a recommended treatment when no contraindications exist, yet it is poorly utilized by women with early surgical menopause. Given women perceived...

Spring 2019

Zuo, Jieyu

Introduction: Traditional Chinese Medicine (TCM) represents one of the first holistic approaches in the world to treat and prevent disease. Herbal medicine is one of the major therapeutic remedy in TCM. It often involves multi-herb therapies instead of single herb preparations. Parallel to...