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Skip to Search Results- 2Hegadoren, Kathleen M.
- 1Adu, Medard Kofi
- 1Al-Ghamdi,Mohammad S
- 1Al-Nuaimi, Saleem K
- 1Amritraj, Asha
- 1Amusan, Precious
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Phasic Electrodermal Activity in Schizophrenia: Skin Conductance Response in Unmedicated Schizophrenic Patients in Comparison to Normal Controls
DownloadSpring 2012
Stimulus-elicited (phasic) skin conductance responses (SCRs) to indifferent stimuli have often been employed to examine abnormalities in orienting (allocation of attention) in studies of schizophrenia. Most previous studies have examined phasic activity only during habituation paradigms....
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Fall 2012
Numerous investigations have suggested that dysregulation of the neurotransmitter glutamate (Glu) plays an important role in certain neuropsychiatric disorders, like depression. Pregnancy and the postpartum period are associated with the most substantial physiological alteration of female...
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Spring 2011
Self-harming behaviours and suicidality are a serious problem in psychiatric patients with major depressive disorder (MDD) and borderline personality disorder (BPD). Suicidal behaviours are sometimes seen as manipulative and attention-seeking in BPD patients, and are therefore not considered as...
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Is Atomoxetine effective in treating nicotine withdrawal? A double-blind, placebo-controlled, fixed-dose study
DownloadFall 2011
Drugs that affect noradrenaline neurotransmission are used as therapy for smoking cessation. A recent study in individuals with attention-deficit and hyperactivity disorder (ADHD) suggested that atomoxetine, a noradrenaline reuptake inhibitor, may reduce cravings in individuals with ADHD who also...
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Fall 2011
Risk factors for postpartum depression (PPD) include history of a major depressive episode, premenstrual dysphoric disorder, or a prior episode of PPD. Fluctuations in estrogen, progesterone, and neuroactive steroids occur in the postpartum, and these molecules act as modulators of a number of...
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Spring 2010
Studies were conducted to investigate relationships between trait emotion regulation variables (including reappraisal and suppression) and selective attention to negative emotional information. Correlation analyses of data in experiment 1 showed that trait-suppression was related to early...
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Spring 2010
Group psychotherapy is the most widely utilized treatment modality for convicted sex offenders, and the therapeutic alliance is considered a fundamental concept in virtually all applications of psychotherapy. However, empirical examination of how the therapeutic alliance impacts upon treatment...
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Fall 2010
Insulin-like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptor is a single trans-membrane glycoprotein that is widely but selectively distributed throughout the central nervous system (CNS). IGF-II/M6P receptor is involved in the trafficking of M6P-containing lysosomal enzymes from the...
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Cellular level/distribution of γ-secretase subunit nicastrin and its modulator p23 in the brain
DownloadSpring 2010
The processing of amyloid precursor protein (APP) by β- and γ-secretases produces amyloid β (Aβ) peptide, the principal component of the neuritic plaques found in Alzheimer’s disease (AD) pathology. The enzyme γ-secretase is a multimeric protein consisting of presenilins-1/2 (PS1/PS2), nicastrin,...
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Fall 2009
In rodents, stress and corticosteroids rapidly increase excitatory neurotransmission. During excitatory neurotransmission, glutamate concentrations are maintained by conversion of glutamine to glutamate. The hypothesis was that cortisol would alter human prefrontal glutamine or glutamate...