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Skip to Search Results- 2Coulombe, Marilyne G.
- 2Kinnaird, Adam
- 2Srivastava, Nutan
- 1Abdualla, Radya Y
- 1Abofayed, Hiatem Abdullah
- 1Aburahess, Salah
- 8Primary Biliary Cholangitis
- 7Inflammatory Bowel Disease
- 7Inflammatory bowel disease
- 6Endothelial cells
- 5Acute myeloid leukemia
- 5Mitochondria
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Assessment of the Utility and Impact of IV Magnesium Infusion on Patient Outcomes and Quality of Life in Acute Heart Failure
DownloadFall 2024
Heart failure (HF) is a complex condition which is a growing and lethal public health issue in Canada and internationally. In the last several decades, the number of treatments for HF with reduced ejection fraction, which makes up a large portion of the HF population, has grown. The recommended...
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Experience of patients with spinal cord injury regarding the quality of care during acute hospital stay in Nepal
DownloadFall 2024
Spinal Cord Injury (SCI) results in physical impairments, psychosocial issues, increased mortality and morbidity that challenge individuals and demand lifelong support, which starts from acute care. Understanding the experience after SCI in acute care is essential as it may impact the Person(s)...
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The Characterization and Assessment of Transition Success in Young Adults with Inflammatory Bowel Disease
DownloadFall 2024
Canada has one of the highest incidence rates of inflammatory bowel disease (IBD) worldwide, particularly among adolescents and young adults. As the incidence of pediatric-onset IBD is projected to increase in the upcoming years, more patients will need to transition from pediatric to adult care....
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Exposure to Allergens and Proinflammatory Mediators Modulate Airway Epithelial Cell Innate Responses, Metabolism, and Physiology
DownloadFall 2024
Lungs and airways health and protection depend on the integrity of airway epithelium. Insulin is a growth hormone that through activation of several signaling pathways play a central role to maintain cellular growth and activate metabolism. Airway epithelium is in constant exposure to inhaled...
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Mechanism and consequences of von Willebrand factor upregulation in response to aging and organ transplantation
DownloadFall 2024
Von Willebrand factor (VWF) is a procoagulant protein, which is crucial for blood clot formation and is exclusively expressed in endothelial cells and megakaryocytes. An unregulated increase in VWF levels is associated with elevating the incidence of thrombosis. Elevated VWF levels are observed...
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Heart Failure Related Outcomes in Patients within a Specialized Clinic-Based Cohort and a Population Level Cohort: Emphasis on Diabetes
DownloadFall 2024
Diabetes mellitus (DM) is a well-established risk factor for adverse prognosis in patients with heart failure (HF). Outcomes in this patient population have not been thoroughly investigated in specialized heart function clinics (HFC). Recently, sodium-glucose cotransporter-2 (SGLT2) inhibitors...
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Fall 2024
The chloride intracellular channel (CLIC) isoform 5A was discovered in a complex with ezrin and actin in placenta microvilli. CLIC5A is also greatly enriched in kidney glomeruli and is essential for assembly of the ezrin/NHERF2/podocalyxin complex at the apical domain of glomerular podocyte foot...