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Spring 2018

Brown, Orain, A

A series of phosphoranimide-supported first-row transition metal clusters were prepared, structurally characterized, and investigated for catalytic hydrogenolysis of carbon-heteroatom bonds. Homoleptic heterocubane clusters, as well as two-dimensional bi- and tetranuclear compounds of manganese,...

Spring 2018

Cao, Yong

Small-molecule metabolites (MW < 1,000 Da) are now emerging as an important type of biomarkers, thanks to the rapid development of systems biology such as metabolomics. Compared to nucleic acids and protein, metabolite is closer to the phenotype. Rapid detection and quantification of metabolites...

Spring 2018

Islam, Muhammad Amirul

Quantum dots (QDs) have drawn substantial attention in multidisciplinary research in science, technology, and biomedicine during the last three decades. However, the toxicity of heavy metals and the depleting earth abundance of some elements common to QDs have prompted the development of...

Fall 2024

Gautam, Tania

Reactive aerosol constituents, including organic peroxides (H2O2, ROOR and ROOH), organosulfates (OS), and organonitrates (ON), are integral components of atmospheric chemistry, climate dynamics, and human health. However, their intricate chemical compositions and dynamic behaviours present...

Fall 2022

Rana, Natasha

The solute carrier (SLC) family of membrane proteins is responsible for the internalization of a variety of essential small molecule compounds such as amino acids, monosaccharides, neurotransmitters, vitamins, as well as many inorganic ions. In recent years, these proteins have been recognized as...

Fall 2022

Bozheng, Sun

The studies of [n]cumulenes have marked the 100th anniversary of Brand’s report of tetraphenylbutatriene in 1921. During the past century, hundreds of different [n]cumulenes have been studied, and [n]cumulenes are depicted as good candidates for the development of novel materials. [n]Cumulenes...

Spring 2021

Nguyen, Kevin

Chiral cyclobutanes are components of numerous bioactive natural products and consequently they have also gained significant attention in medicinal chemistry. Optically enriched cyclobutylboronates can serve as valuable synthetic intermediates for the synthesis of a broad variety of chiral...

Spring 2018

Han, Wei

Blood-metabolite-based biomarkers are useful for the early-stage diagnosis, accurate prognostic prediction and personalized treatment of various diseases. Blood contains a massive number of metabolites that can potentially become biomarkers, but the metabolome coverage of current analytical...

Spring 2018

Wei, Menglian

Surface plasmon resonance (SPR) has emerged as a powerful tool in sensing and biosensing for decades due to its label free and real-time data collection characteristics. In the first part of this thesis, a custom-built high performance SPR spectrometer with broad range of scanning angle, high...

Fall 2017

Towle, Kaitlyn M.

Enterocin 7 is a two-component, leaderless bacteriocin comprised of an A and B peptide and produced by Enterococcus faecalis 710C. The secondary structure of enterocin 7B was investigated through circular dichroism. A high degree of α-helicity was discovered by circular dichroism, regardless of...