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Skip to Search Results- 2Li, Leo
- 2Nizio, Katie D
- 1Abdel Latif Ibraheem, Ahmed Abdel Mohsen
- 1Abdelfattah, Ahmed
- 1Abel, Robin Jacob
- 1Abou-Ghanem, Maya
- 33Mass-spectrometry
- 23Organic compounds. Synthesis.
- 21Capillary electrophoresis.
- 21Catalysis
- 21Chemistry
- 20Metabolomics
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Fall 2014
Carbohydrate–protein interactions play key roles in a range of biological processes. Noticeable advancements have been made in understanding the features associated with the recognition of pyranosides (six-membered ring sugars) by proteins. In contrast, similar detailed studies about the...
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New Approaches to Thermodynamics-based Predictive Modelling of Gas Chromatography and Comprehensive Two-dimensional Gas Chromatography
DownloadSpring 2019
Thermodynamics-based predictive models of retention in gas chromatography and comprehensive two-dimensional gas chromatography have been demonstrated to provide high prediction accuracy across a wide range of separation conditions. They generally predict better than retention index-based models...
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Isolation of Reactive Bonding Environments in the Main Group via New Donor-Acceptor and Kinetic Stabilization Pathways
DownloadSpring 2013
The research presented in this Thesis is focused on the synthesis of highly reactive molecules featuring Group 14 elements with the aim of discovering new bonding environments which can be translated into new forms of reactivity. Kinetic stabilization with the use of sterically demanding ligands...
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Studying Protein–Glycolipid Interactions and Membrane Peptides and Proteins using Electrospray Ionization Mass Spectrometry and Model Membranes
DownloadFall 2018
Membrane systems, including glycolipids (GLs) and membrane peptides and proteins (MPs), play an important role in many cellular processes, such as singling, cellular recognition, transportation, and energy conversion. However, the amphipathic nature of GLs and MPs makes their analysis...
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Targeting Breast Cancer: Synthesis and Biological Evaluation of Novel D-Fructose Based Molecular Imaging Agents And Cytotoxic Noscapine Analogues
DownloadFall 2017
Among the characteristic hallmarks of cancer cells is their high replicative potential, which in turn leads to the overexpression of the facilitative hexose transporters (GLUTs) to provide the energy required for cell growth and proliferation. Interestingly, in 1996 the major D-fructose...
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Fall 2014
The development of therapeutics to target dendritic cells (DCs) for the treatment of diseases is of great importance, as these cells are known to play an important role in antigen processing and presentation in the immune system. Herein, we explore the applications of biocompatible,...
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Spring 2015
In this thesis, we simulated the resonance Raman spectra of uracil and its derivatives, including 5-halogenated (F, Cl, Br) uracils and thymine, using the Herzberg-Teller short-time dynamics formalism. The electronic structure calculations are carried out using density functional theory (DFT) for...