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Skip to Search Results- 20Spinal cord injury
- 9Walking
- 4Functional electrical stimulation
- 3Rehabilitation
- 2Balance
- 2Corticospinal tract
- 1Alvarado, Laura
- 1Bamford, Jeremy, Andrew
- 1Bergquist, Austin J
- 1Cheng,Cheng
- 1Clair, Joanna
- 1D'Amico, Jessica M
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Fall 2021
Spinal cord injury (SCI) not only leads to motor and sensory dysfunction, but just as debilitating are secondary consequences of SCI such as bowel disorders, neuroinflammation, immune suppression, pain and psychiatric disorders. In this thesis, I explore multiple aspects of recovery after SCI in...
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Spring 2019
Walking is a locomotor task that integrates information from all over the nervous system. The lumbosacral spinal cord houses neural networks that contribute to locomotion. These networks dominate locomotor activity during development and may provide suitable targets for restoring function after...
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Fall 2018
Physical training can affect the excitability of spinal reflexes in a training-specific manner in uninjured humans. Therefore, the first part of this thesis examined the changes in the excitability of a polysynaptic and a monosynaptic reflex in an ankle plantarflexor, after contrasting forms of...
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Fall 2017
Spinal cord injury (SCI) is an extremely debilitating condition, leading to sensory and motor dysfunction below the level of the injury. Presently, there are few effective treatments for SCI. This is in part due to the immense complexity of SCI pathophysiology. Thus, combined research approaches...
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Fall 2015
Inhibitory feedback from sensory pathways is important for controlling movement. In this thesis we characterize a long-latency inhibitory spinal pathway to ankle flexors that is activated by low-threshold, homonymous afferents. In non-injured participants, this pathway was activated by both...
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Fall 2013
This thesis explores strategies to promote neuronal plasticity in a rat model of cervical spinal cord injury (SCI) in an effort to achieve improved recovery of skilled forelimb use. I focused on investigating how motor pathways disrupted by an SCI may connect to spared, lesion-bridging relay...
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Peripheral and central contributions to evoked contractions during neuromuscular electrical stimulation
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The present thesis examined two general questions regarding neuromuscular electrical stimulation (NMES): 1) How can the delivery of NMES be optimised to enhance synaptic motor unit recruitment via reflex pathways (central pathways) and 2) Can motor unit recruitment through central pathways...
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A pilot study investigating arm and leg FES-assisted cycling as an intervention for improving ambulation after Incomplete Spinal Cord Injury
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People with incomplete spinal cord injury (iSCI) have the potential for recovering walking through plasticity-induced changes in the remaining neural circuitry. Current rehabilitation for walking attempts to induce such changes by providing relevant sensory inputs and motor commands through...
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Neuronal Mechanisms of Hyperexcitability in Individuals with Spasticity after Spinal Cord Injury and Individuals with Bruxism
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Motoneuron hyperexcitability is a characteristic of several different motor disorders. We examined neuronal mechanisms of hyperexcitability in two of these disorders: spasticity after spinal cord injury (SCI) and bruxism. Involuntary muscle spasms after SCI occur as a result of uncontrolled...