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Skip to Search Results- 1Ajamian, Farnam
- 1Alzaben, Abeer Salman
- 1Archibald, Mandy M
- 1Aung, Yin N
- 1Bahreinian, Salma
- 1Drall, Kelsea Michelle
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Fall 2023
Infants and children require a net positive calcium (Ca2+) balance to achieve optimal bone mineral density by early adulthood. Vitamin D is a hormone that increases blood Ca2+ levels by increasing intestinal absorption and renal reabsorption of Ca2+ as well as bone remodelling. In both the kidney...
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An Exploration of the Associations Between Gut and Serum Immunoglobulin A in Infancy and Asthma in Childhood
DownloadSpring 2020
Introduction Early immune maturation and gut microbial composition have a clear impact on the development of asthma and atopy in children. There is a large body of evidence on the association between immunoglobulin A (IgA), asthma, and other atopic diseases. Low secretory Immunoglobulin A (sIgA)...
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Mapping intracellular cytokine pools in granulocytes: Dynamic storage and trafficking sites of interleukin-9 and interleukin-13 in human eosinophils
DownloadFall 2020
Eosinophils are immune cells with constantly evolving roles in both innate and adaptive immunity and have long been associated with the predominant pathology of the human airways, asthma. Eosinophils are specialized in their granulocytic nature, possessing several membrane-bound secretory...
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Pea Protein Based Nanoemulsions for Delivery of Vitamin D: Fabrication, Stability and In vitro Study using Caco-2 Cells
DownloadFall 2019
In North America, a significant population is vitamin D deficient due to insufficient sunlight exposure in winters. Increasing research has shown that vitamin D, apart from its skeletal functions, also has potential to lower the risk of chronic diseases such as autoimmune disorders, diabetes...
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Understanding the role of Clostridioides difficile and Vitamin D supplementation in shaping the gut microbiome of Canadian infants
DownloadSpring 2019
Introduction: The gut microbiome is shaped during infancy and has an important role in the development of both the immune and metabolic systems. Many early life exposures and events contribute to the composition of this complex intestinal environment, notably early infant diet and breastfeeding....
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Spring 2018
Introduction: Asthma is a chronic inflammatory disease characterized by intermittent episodes of acute airway inflammation and bronchoconstriction. Although asthma is generally considered a disease of the airways, asthma is also associated with an increased risk of developing cardiovascular (CV)...
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Vitamin D Status and Markers of Cardiometabolic and Liver Disease Risk in Childhood Obesity
DownloadSpring 2017
Vitamin D insufficiency is highly prevalent in children (up to 40%), particularly in northern climates such as Alberta, due to reduced sunlight exposure and low intake. Although suboptimal vitamin D status and metabolic dysregulation are commonly observed in obesity, little is known about the...
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Calcium and Vitamin D Intake During Pregnancy and Postpartum in the Alberta Pregnancy Outcomes and Nutrition (APrON) Study
DownloadFall 2016
Calcium and vitamin D are important in maintaining a healthy pregnancy. Low intake/status has been associated with preeclampsia, preterm delivery, lower birth weight, poor fetal skeletal growth, reduced bone mass, and excessive maternal bone loss. Rarely have these nutrients been examined...
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An Analysis of the Environmental Risk Factors of Childhood Asthma and Asthma-like Symptoms: Results from the National Longitudinal Survey of Children and Youth
DownloadSpring 2016
It is known that a multitude of environmental factors are implicated in the incidence of asthma and asthma symptoms among children; however, previous research has provided inconsistent and/or insufficient evidence as to whether residing in a farming environment during childhood can lead to a...
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The prevalence and determinants of adequate vitamin D intake and supplementation among Canadian children
DownloadFall 2016
Most Canadian children are not meeting the dietary recommendations for vitamin D and have not enough sun exposure to synthesize vitamin D in their skin. Vitamin D supplementation therefore seems a necessity. However, no study has examined whether vitamin D from diet and supplements combined is...