SearchSkip to Search Results
- 1 Owttrim, George W.
- 1Anderson, Bailey
- 1Chen, Elizabeth J. Y.
- 1Fagan-Garcia, Katharine
- 1Griffiths, Cameron
- 1Hokowhitu, Brendan
- 8Graduate Studies and Research, Faculty of
- 8Graduate Studies and Research, Faculty of/Theses and Dissertations
- 2WISEST Summer Research Program
- 2WISEST Summer Research Program/WISEST Research Posters
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Journal Articles (Biological Sciences)
Poxviruses encode many genes that are orthologs of cellular genes. These orthologs serve many functions, but those that are of most interest are ones that have evolved further and now serve an immune-evasion function. Such genes were likely first acquired by poxviruses through some form of...
Respiratory syncytial virus (RSV) is a ubiquitous respiratory pathogen that infects almost everyone by the age of two. In high-risk populations, such as infants and elderly individuals, RSV can infect the lower respiratory tract and cause severe symptoms, such as bronchiolitis or pneumonia. As a...
Infectious respiratory diseases, caused by viruses and bacteria that attack the respiratory system, constitute a serious threat in public health around the world. Pathogens can be transmitted in the air though large droplets or aerosols. As aerosols can linger in the environment for a prolonged...
Inhibition and enhancement of Respiratory Syncytial Virus replication by nucleoside analogues and bis(indole) compoundsDownload
Respiratory syncytial virus (RSV) is an Orthopneumovirus that infects the epithelium of the airways. Severe RSV infection of the lower respiratory tract in infants is a leading cause of pediatric hospitalizations. RSV also causes substantial morbidity in immunocompromised and elderly populations....
Virus Induced Asthma Exacerbations: Immunologic Mechanisms and Metabolomic Biomarkers
Asthma is a complex multifaceted chronic inflammatory disease that is characterized clinically by reversible airflow obstruction, shortness of breath, coughing, and wheezing. Asthma is the most common chronic disease in children, and is differentiated into many phenotypes with multiple triggers....
This thesis examines the pathophysiology of asthma, attempts to determine the cellular mechanisms behind viral-induced immune memory mediated asthma exacerbations, and investigates urinary metabolomic biomarkers of asthma and neonatal hypoxia.
The introduction of WNV into North America in 1999 was followed by rapid spread throughout the continent. Today, WNV is an endemic pathogen in the west, with thousands of cases of severe infection reported annually. In addition to traditional vaccine research, there is an urgent need to...
Invited major book review of M. Cannon & L. Sunseri, (2011), “Racism, Colonialism, and Indigeneity in Canada: A Reader”Download
Book Review: Racism, Colonialism, and Indigeneity in Canada: A Reader, Edited by Martin J. Cannon and Lina Sunseri. Toronto: Oxford University Press Canada, 2011, paperback, 284 pages. ISBN 978-0-1954-3231-2