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- 40Asthma
- 15Randomized Controlled Trials as Topic
- 10Acute Disease
- 8Anti-Asthmatic Agents
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- 39Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
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An Exploration of the Associations Between Gut and Serum Immunoglobulin A in Infancy and Asthma in Childhood
DownloadSpring 2020
Introduction Early immune maturation and gut microbial composition have a clear impact on the development of asthma and atopy in children. There is a large body of evidence on the association between immunoglobulin A (IgA), asthma, and other atopic diseases. Low secretory Immunoglobulin A (sIgA)...
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Mapping intracellular cytokine pools in granulocytes: Dynamic storage and trafficking sites of interleukin-9 and interleukin-13 in human eosinophils
DownloadFall 2020
Eosinophils are immune cells with constantly evolving roles in both innate and adaptive immunity and have long been associated with the predominant pathology of the human airways, asthma. Eosinophils are specialized in their granulocytic nature, possessing several membrane-bound secretory...
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Spring 2018
Introduction: Asthma is a chronic inflammatory disease characterized by intermittent episodes of acute airway inflammation and bronchoconstriction. Although asthma is generally considered a disease of the airways, asthma is also associated with an increased risk of developing cardiovascular (CV)...
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Spring 2018
Background: Overviews of reviews of healthcare interventions (overviews) compile information from multiple systematic reviews (SRs) to provide a single synthesis of relevant evidence for health-care decision-making. Their increasing popularity, combined with a lack of evidence-based guidance for...
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Patient-reported outcome measures for adverse events: A systematic review and COSMIN evaluation study
DownloadFall 2017
ABSTRACT Background: Health care requires constant improvement. Harms in health care are becoming a priority, as is incorporating the patient’s voice in both clinical research and clinical care. Patients have been found to provide a more subjective, detailed perspective of their treatment...
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2017-10-20
Azad-Khaneghah, Peyman, Neubauer, Noelannah, Stroulia, Eleni, Liu, Lili
Objectives: 1. To identify items used in peer reviewed mobile app rating scales. To identify factors important to patients, clinicians, and app developers in evaluating the quality of mental health apps.
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Advancing knowledge of rapid reviews: an analysis of results, conclusions and recommendations from published review articles examining rapid reviews
Download2016
Featherstone, Robin, Paynter, Robin , Guise, Jeanne-Marie, Umscheid, Craig, Mitchell, Matthew , Robinson, Karen, Dryden, Donna, Foisy, Michelle, Hartling, Lisa
Background: Rapid review (RR) products are inherently appealing as they are intended to be less time-consuming and resource-intensive than traditional systematic reviews (SRs); however, there is concern about the rigor of methods and reliability of results. In 2013 to 2014, a workgroup comprising...
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Developing a Patient-Driven Arts-Based Knowledge Translation Tool for Parents of Children with Asthma
DownloadSpring 2016
Background: Family-centered education is critical to managing childhood asthma, the most common chronic disease of childhood in North America. Parents are largely responsible for the day-to-day management of their child’s asthma; as such, finding effective ways to educate parents about asthma is...
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Outdoor Air Pollution and Children´s Asthma in the Census Metropolitan Area of Edmonton, Alberta: the Influence of Place of Residence and Socioeconomic Position
DownloadFall 2016
Background: Asthma is the most common chronic respiratory disease in children and air pollution has been implicated in its development and exacerbations worldwide. The Census Metropolitan Area of Edmonton (CMAE), Alberta, has unique air pollution sources (traffic and industrial related air...