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Skip to Search Results- 11Wishart, D.S.
- 8Stothard, Paul
- 8University of Alberta, Department of Biological Sciences
- 6Stothard, P.
- 6Wang, J.
- 5Li, John
- 40Biological Sciences, Department of
- 33Graduate and Postdoctoral Studies (GPS), Faculty of
- 33Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 32Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 11Agricultural, Food and Nutritional Science, Department of
- 11Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Investigating the Nuclear Roles of Iron Regulatory Protein-1A (IRP1A) in Drosophila melanogaster
DownloadFall 2023
Iron is an indispensable micronutrient for almost all organisms. Either the lack or excess of iron can result in various human diseases. Therefore, to maintain cellular iron homeostasis, the IRP/IRE (iron regulatory protein/iron responsive element) system tightly regulates iron concentrations....
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Spring 2023
Intestinal epithelial damage and homeostatic cell shedding sends evolutionarily conserved growth signals to activate division programs in stem cells, which renews the epithelium to maintain barrier integrity. In addition to conserved growth and stress signaling, microbes and innate immune...
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Fall 2022
The ppk20 (pickpocket 20) gene was identified from a two-step screen that was aimed at identifying genes relevant to Drosophila iron and heme homeostasis. Initially, our lab collaborated with two other labs and carried out a prothoracic gland (PG)-specific genome-wide screen of 12,500 RNA...
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Characterization of the crosstalk between immunity and metabolism in Drosophila melanogaster model
DownloadFall 2021
Immune and metabolic pathways collectively contribute to the containment of microbial invaders, and persistent activation of immune responses contribute to the development of severe metabolic disorders. To determine how interaction between innate immune system and metabolic responses affected...
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Regulation of digestive tract and progenitor cell homeostasis by intestinal bacteria in Drosophila melanogaster
DownloadFall 2020
The digestive tract facilitates nutrient uptake in the presence of a heterogenous cohort of symbiotic microbes. These microbes along with their collective genetic material form the intestinal microbiome and contribute to animal phenotypes. Similar to mammals, the microbiome of insects forms a...
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Spring 2020
The web contains a large volume of tables that provide structured information about entities and relationships. This data may be used as a source for exploratory searches and to gather information about desired entities. This thesis focuses on one particular exploratory search where given a query...
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Fall 2020
Peroxisomes are organelles responsible for processing lipids and managing reactive oxygen species. A conserved family of genes called peroxisome biogenesis factors (Peroxin, Pex) encode proteins necessary for peroxisome biogenesis and function. In yeast and mammals, PEROXIN7 (PEX7) acts as a...
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Spring 2019
Organelles serve to compartmentalize biochemical functions within the eukaryotic cell. However, to collectively maintain cellular homeostasis, organelles must communicate in some way in order to coordinate these functions. Two such organelles,the peroxisome and the lipid droplet, are both...
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2018
University of Alberta, Department of Biological Sciences
This image is part of a series displaying seperating fruit flies into 4 groups based on phenotypic characteristics. Fruit fly experiments are performed in Molecular Genetics and Heredity: Biology 207. This image was created as part of the University of Alberta OER image database project in...