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Subject / Keyword
- 21Pharmacokinetics
- 21Rats--Physiology
- 4Enantiomers
- 4Nonsteroidal anti-inflammatory agents
- 3Muscles--Metabolism
- 2Biodistribution
Author / Creator / Contributor
- 1Al Lawati, Hanan M
- 1Bhatti, Muhammad Masood.
- 1Binkhathlan, Ziyad
- 1Carr, Robert Arthur.
- 1Chang, J.
- 1Chen, Zhong-Xiao.
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- 19Faculty of Pharmacy and Pharmaceutical Sciences
- 4Department of Medicine
- 4Department of Pharmacology
- 3Department of Physiology
- 2Department of Medical Sciences
- 1Department of Animal Science
Supervisors
- 1Brocks, Dion R. (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Dr. Andrew Holt
- 1Dr. Brocks, Dion R (Faculty of Pharmacy and Pharmaceutical Sciences
- 1Dr. Dion R. Brocks, Faculty of Pharmacy and Pharmaceutical Sciences
- 1Jamali, Fakhreddin ( Pharmacy and Pharmaceutical Science)
- 1Jamali, Fakhreddin (Faculty of Pharmacy and Pharmaceutical Sciences)
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The effects of hyperlipidemia on the pharmacokinetic and pharmacodynamic aspects of amiodarone and ketoconazole
DownloadFall 2010
The influence of hyperlipidemia on the pharmacodynamic and pharmacokinetic aspects of lipophilic drugs was explored. The antiarrhythmic, amiodarone, and the antifungal, (±)-ketoconazole, were used as model drugs. Experimental hyperlipidemia was induced in rat using poloxamer 407 and two sensitive...
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