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Skip to Search Results- 6Dosimetry
- 4Radiation therapy
- 1Automated treatment plans
- 1Brachytherapy
- 1Branch and bound algorithm
- 1Cancer
- 1Anderson, Danielle L.
- 1Babadagli, Mustafa E
- 1Liu, Derek MC
- 1Liu, Weiyang
- 1Morielli, Andria R.
- 1Morrison, Hali A.E.K.
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Fall 2015
With the advent and development of hybrid Linac-MR technology, we will be able to track and treat lesions in real time. This will permit the narrowing of radiotherapy margins and escalation of dose, augmenting the therapeutic outcome of radiotherapy. The addition of a magnetic field to the...
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Fall 2010
Real time image guided radiotherapy has been proposed by integrating an in-line 6 MV linear accelerator (linac) to a magnetic resonance (MR) imager in either a parallel or transverse configuration. In either configuration, magnetic interference in the linac is caused by its immersion in the...
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Fall 2014
The dissertation explores some of the limitations and assumptions in the current approach to permanent prostate brachytherapy (PPB) dosimetry. Where possible, novel insights and practical improvements are proposed, which aim to enhance the accuracy of radiation dose delivery during treatment. The...
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Accurate Dosimetry for Ocular Brachytherapy: Measurement, Delivery Uncertainty, and Dose Calculation Studies
DownloadFall 2017
Ocular brachytherapy has been found to be an excellent alternative for the treatment of ocular melanomas compared to the predominantly used treatment prior to the 1980s of enucleation. Tumour control rates are generally >90%, overall survival rates are equivalent to enucleation, and ocular...
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Fall 2010
This thesis encompasses the development and testing of an interstitial photodynamic therapy (iPDT) system for the treatment of prostate cancer. It begins with the optical characterization of a novel photosensitizer (SL-052) followed by a study of tissue optics as it applies to iPDT. The design...
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Fall 2020
Background: A standard treatment option for locally advanced rectal cancer includes 5-6 weeks of neoadjuvant chemoradiation (NACRT) followed by surgery about 6-8 weeks later. NACRT improves outcomes for rectal cancer patients but also causes acute toxicities which may impede quality of life...
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A Mixed Integer Linear Programming Optimization Model for Capturing Expert Planning Style in Interstitial Low Dose Rate Prostate Brachytherapy
DownloadSpring 2017
Low dose rate (LDR) brachytherapy is a minimally invasive form of radiation therapy, used to treat prostate cancer, and it involves permanent implantation of radioactive sources (seeds) inside of the prostate gland. Treatment planning in brachytherapy involves a decision making process for the...
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Fall 2012
A radiation detector geared towards megavoltage external beam radiotherapy has been developed using a liquid scintillator and a charge coupled device (CCD). The liquid scintillator used is BetaMax ES (MP Biomedicals, Santa Ana, CA) and the CCD comes from an SPC880NC webcam (Royal Philips...
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Dosimetry and Biological Studies for Microbeam Radiation Therapy at the Canadian Light Source
DownloadFall 2015
Microbeam radiation therapy (MRT) is a pre-clinical type of radiation therapy that uses an array of high-dose microbeams to treat solid tumours. An intense, quasi-parallel synchrotron beam is collimated to create microbeams several 10s of μm wide, and separated by 100s of μm. Animal studies...