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Skip to Search Results- 1Aghamohammadi Sereshki, Arash
- 1Bernard-Gauthier, Vadim
- 1Bhardwaj, Paramjit P
- 1Chapman, David W
- 1Fahreen, Rajani I.
- 1Ferdousi, Mehnaz I
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Exploring the Relationship Between Depression and Adherence in Individuals with Type 2 Diabetes
DownloadFall 2020
Background: Depression is a well-known risk factor for poor medication adherence in individuals with diabetes; however, this association is based on cross-sectional and cohort studies measuring adherence after depression is diagnosed. Symptoms of depression often progress before medical...
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Characterization of transport of positron emission tomography tracer 3′-deoxy-3′-fluorothymidine by nucleoside transporters
DownloadFall 2012
Positron emission tomography (PET) tracer 3′-fluoro-3′-deoxythymidine (FLT) is used for imaging tumor proliferation. Prior to this work, human equilibrative nucleoside transporter 1 (hENT1) was the only known human nucleoside transporter (hNT) capable of FLT transport. The aim of this research...
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Depression of Lead-activated Sphalerite by Sodium Hydrogen Phosphate for Red Dog Mine Operation
DownloadSpring 2019
The inadvertent activation of sphalerite by lead ions have been noticed and studied for decades. In this study, flotation behavior of sphalerite upon lead activation was studied. Sodium hydrogen phosphate was applied as a main depressant to test its effect on improving Pb-Zn selectivity. Surface...
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Hippocampal neuroplasticity and neurogenesis in major depressive disorder: a high field MRI study
DownloadFall 2012
The hippocampus is a brain structure responsible for memory, learning, and the stress response; it is also used as a model for major depressive disorder (MDD) in preclinical studies. Preclinical models have shown that the hippocampal subfields are differentially affected by chronic stress....
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Structure-Affinity Relationship Study of Novel Imidazoline Ligands at Imidazoline Binding Sites and α-Adrenoceptors
DownloadFall 2014
Many drugs containing an imidazoline moiety are thought to bind to both imidazoline binding sites (IBS) and α-adrenoceptors (α-AR) to mediate their therapeutic effects. To aid in better characterisation of these binding sites, the structure-affinity relationships of several new series of...
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Fall 2015
This thesis consists of 2 closely linked projects that evaluate the importance of depressive symptoms (hereafter, for brevity, referred to as “depression”) for short-term prognosis after general medical hospitalizations. Project 1 systematically reviews the literature to examine whether...
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Spring 2017
Coronary artery disease (CAD) is the leading cause of mortality in developed countries, followed by depression. Recent literature supports a bidirectional relationship between depression and CAD, which adversely affects the quality of life. Although there is a high prevalence of co-occurring CAD...
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Variation in in vivo prefrontal GABA, glutamate and glutamine – effects of reproductive factors, cortisol and major depressive disorder
DownloadFall 2017
Variations in glutamate and γ-aminobutyric acid (GABA), excitatory and inhibitory amino acid neurotransmitters in the brain, have been linked with cyclical changes across the menstrual cycle and in stress and stress-related mental disorders. We used 3.0 Tesla proton magnetic resonance...
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Links Between Depressive Symptoms, Sexual Communication, and Sexual Satisfaction Across Three Years
DownloadSpring 2021
Guided by a relational developmental systems perspective, stress generation hypothesis, and gender relations theory, this thesis examined two major research questions: (1) What are the longitudinal associations between self-reported depression symptoms, sexual communication, and sexual...
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Structural changes of the amygdala subnuclei and limbic white matter tracts in healthy aging and major depressive disorder
DownloadFall 2019
The world population is dramatically aging. Several factors affect brain in healthy aging. The apolipoprotein E (APOE), brain-derived neurotrophic factor (BDNF) and catechol-O-methyl transferase (COMT) might be involved in neurodegenerative diseases, depression and cognitive decline in healthy...