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- 26Graduate Studies and Research, Faculty of
- 26Graduate Studies and Research, Faculty of/Theses and Dissertations
- 9Medicine and Dentistry, Faculty of
- 9Medicine and Dentistry, Faculty of/Alberta Research Centre for Health Evidence (ARCHE)
- 5University of Alberta Libraries
- 4University of Alberta Libraries/Libraries Staff Publications
Industrial emissions and Children’s Environmental Injustice in Canada: Exploring geographical patterns and an example of its relation to Children’s Cancer in ManitobaDownload
Background: Environmental Injustice (EI) suggests that socioeconomically disadvantaged citizens/minority groups have a higher than average exposure to environmental contaminants and bear more subsequent health risks than their socioeconomically advantaged/majority group counterparts. In order to...
Background: Bias is a significant concern in pediatric randomized controlled trials (RCTs), but while there have been numerous calls for improvement in trial conduct, traditional means of education and dissemination of methodological principles have not had a substantial effect on the quality of...
Profiles of Systemic Inflammatory Response Indicated by C-reactive protein in Children Undergoing Ventricular Assist Device Support and Heart TransplantationDownload
C-reactive protein (CRP) is a biomarker of systemic inflammatory response (SIR) which is associated with the extent and activity of disease. The profiles of SIR and the changes of CRP remain unknown in children undergoing ventricular assist device (VAD) support and heart transplantation (HTx). We...
B cell Tolerance Mechanisms Following ABO-incompatible Infant Heart Transplant: A Potential Role for CD22Download
Due to presumed immune immaturity, infants are able to accept heart transplants across the ABO barrier, a procedure that would result in catastrophic consequences if performed in adults. Our group has demonstrated that following ABO-incompatible heart transplantation (ABOi HTx), infants develop...
Background: The use of long-term non-invasive ventilation (NIV), defined as the provision of respiratory support from the upper airway through a mask interface, has increased in infants and older children over the past two decades. A number of studies have been published on NIV use in the overall...
Systematic Review of Knowledge Translation Strategies to Promote Research Uptake in Child Health SettingsDownload
Background: Strategies to assist evidence-based decision-making for healthcare professionals are crucial to ensure high quality patient care and outcomes. The goal of this systematic review was to identify and synthesize the evidence on knowledge translation interventions aimed at putting...
A descriptive analysis of child-relevant systematic reviews in the Cochrane Database of Systematic ReviewsDownload
Background: Systematic reviews (SRs) are considered an important tool for decision-making. There has been no recent comprehensive identification or description of child-relevant SRs. A description of existing child-relevant SRs would help to identify the extent of available child-relevant...
Infant face and throat replicas are used in research laboratories to compare the effectiveness of different valved holding chamber and face mask designs. The use of soft face models is thought to provide a better representation of mask dead volume and face mask seal than hard face models....
Do health care institutions value research? A mixed methods study of barriers and facilitators to methodological rigor in pediatric randomized trials.Download
Background Pediatric randomized controlled trials (RCTs) are susceptible to a high risk of bias. We examined the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials. Methods We used a mixed methods design, with semi-structured interviews building...