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Skip to Search Results- 14Graduate and Postdoctoral Studies (GPS), Faculty of
- 14Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 2Oil Sands Research and Information Network (OSRIN)
- 2Oil Sands Research and Information Network (OSRIN)/OSRIN Technical Reports
- 1Agricultural, Food and Nutritional Science, Department of
- 1Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Department of Biological Sciences
- 3Medical Sciences-Laboratory Medicine and Pathology
- 2Department of Oncology
- 1Department of Agricultural, Food, and Nutritional Science
- 1Department of Medicine
- 1Faculty of Physical Education and Recreation
- 2Baracos, Vickie (Oncology)
- 2Damaraju, Sambasivarao (Laboratory Medicine and Pathology)
- 2Putman, Charles (Physical Education and Recreation)
- 1Ali, Declan W. (Biological Sciences)
- 1Baracos, Vickie (Oncology & Agricultural, Food, and Nutritional Science)
- 1Boucher, Yan (Biological Sciences)
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Zebrafish embryos exposed to alcohol undergo abnormal development of motor neurons and muscle fibers
DownloadFall 2009
Children with Fetal Alcohol Spectrum Disorder have significantly delayed motor skills, and deficiencies in reflex development. The reasons underlying these motor deficits are not fully understood. The purpose of this thesis was to investigate the effect of embryonic exposure to ethanol (EtOH) on...
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Maternal and Paternal Genomes Differentially Affect Myofibre Characteristics and Muscle Weights of Bovine Fetuses at Midgestation
Download2013
Kruk, Z. A., Xiang R., Rutley, D. L., Thomsen, D. A., Anderson, G. I., Fitzsimmons, C., Ghanipoor-Samami, M., Hiendleder, S., Roberts, C. T., Eindorf, T., Burns, B. M., Greenwood, P. L., Johns, W. H.
Postnatal myofibre characteristics and muscle mass are largely determined during fetal development and may be significantly affected by epigenetic parent-of-origin effects. However, data on such effects in prenatal muscle development that could help understand unexplained variation in postnatal...
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Combined Assembly of Metagenomic Libraries from The Faecal Samples of IBD and PSC Patients Allowed The Identification of African Swine Fever Virus-like Sequences
DownloadSpring 2015
Metagenomics is an emerging discipline to explore microbial diversity in clinical samples, independent of the limitations of cell cultures. This method is widely accepted as a modern technique to detect novel viruses in clinical and environmental samples and has the potential to contribute to the...
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Single-nucleotide polymorphism discovery in Leptographium longiclavatum, a mountain pine beetle-associated symbiotic fungus, using whole-genome resequencing
Download2014-01-01
Ojeda, Dario I., Dhillon, Braham, Tsui, Clement K. M., Hamelin, Richard C.
Single-nucleotide polymorphisms (SNPs) are rapidly becoming the standard markers in population genomics studies; however, their use in nonmodel organisms is limited due to the lack of cost-effective approaches to uncover genome-wide variation, and the large number of individuals needed in the...
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Profiling and Identification of Post-Transcriptional Regulatory Molecules for Human Cancer Cachexia
DownloadSpring 2017
Cancer cachexia (CC) is a multifactorial syndrome characterized by severe depletion of skeletal muscle, with or without fat loss. A majority of cancer patients with incurable cancer are affected with cachexia and it remains an unmet medical need. Gene expression changes at the transcriptional...
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Elevated Fatty Acid Content in Muscle is Prevented by EPA and DHA in an Animal Model of Colorectal Cancer Receiving CPT-11 / 5-FU
DownloadFall 2012
This study aimed to assess the effect of irinotecan / 5-fluorouracil treatment on amount and types of fatty acids in skeletal muscles of tumor-bearing rats fed: a) control diet, b) fish oil diet. Rats bearing the Ward colorectal carcinoma were fed a semi-purified diet with or without fish oil...
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Fall 2013
Cancer cachexia is a multifactorial syndrome characterized by involuntary weight loss, wasting of skeletal muscle driven by reduced food intake and abnormal metabolism. Cachexia has a negative impact on quality of life, response to chemotherapy and survival. Cachexia research is undeveloped with...
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Fall 2009
Skeletal muscle is a heterogeneous, multinucleated, post-mitotic tissue that contains many functionally diverse fibre types that are capable of adjusting their phenotypic properties in response to altered contractile demands. This plasticity, or adaptability of skeletal muscle is largely...
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Fibre-Type Specific Nuclear Localisation Patterns of NFAT-isoforms in CLFS Induced Skeletal Muscle Adaptations
DownloadSpring 2014
The purpose of this investigation was to characterize the nuclear localisation patterns of NFAT-c1, -c2, -c3, and -c4 in relation to chronic low-frequency stimulation induced fibre type transitions. A model has been suggested to describe the roles of all 4 NFAT isoforms in activity-dependent...