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- 31Graduate Studies and Research, Faculty of
- 31Graduate Studies and Research, Faculty of/Theses and Dissertations
- 6Pharmacy and Pharmaceutical Sciences, Faculty of
- 6Pharmacy and Pharmaceutical Sciences, Faculty of/Journal Articles (Pharmacy)
- 3Chemistry, Department of
- 3Chemistry, Department of/Journal Articles (Chemistry)
Aquatic organisms are susceptible to waterborne nanoparticles and there is only limited understanding of the mechanisms by which these emerging contaminants affect biological processes. The unique properties of nanomaterials necessitate evaluation of standard toxicity testing techniques to...
Cell-electronic Sensing of Cellular Responses and Toxicity Induced by Nanoparticles and Arsenic SpeciesDownload
We demonstrate the development of a real-time cell analysis (RTCA) platform for studying nanoparticle- and arsenic-induced cytotoxicity with potential applications to risk assessment, environmental toxicity monitoring, and drug development. RTCA is an impedance-based in vitro detection system...
The purpose of this project was to formulate, modify and evaluate nanoparticles for targeting asialoglycoprotein receptor found in large numbers exclusively on hepatocyte surfaces. Our goal is to increase the efficacy, reduce the side effects and the cost of the hydrophilic drugs administered to...
A new aerosol particle classiﬁer, the Aerodynamic Aerosol Classifier (AAC), is presented with some of its applications. The instrument uses a centrifugal force and sheath flow between two concentric rotating cylinders to produce a monodisperse aerosol classified by aerodynamic diameter. Since...
Dendritic cells (DCs) play a central role in shaping antigen-specific immune response. Antibody-mediated antigen targeting to DC-specific surface receptors is a promising approach to enhance vaccine efficacy. The objective of this thesis was to develop DC-targeted nanoparticulate formulations for...
Anisotropic particles have generated an enormous amount of research interest due to their applications for drug delivery, electronic displays and as micromotors. However, up till now, there is no single protocol capable of generating particles of “patchy” composition with a variety of...
Third-generation optoelectronics, which utilize nanoscale materials, have received a considerable amount of attention in the chemical sciences and are poised to make a large impact in both fundamental research and real-world application. In order to make a contribution to the field, this thesis...
Chicken feathers are byproduct of poultry industries and except some minor low end application, they are generally dumped into landfills. An effort has been made to utilize this by-product by transforming them into nano-reinforced bioplastics which is not only a solution to feather waste disposal...