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Skip to Search Results- 23Breast Cancer
- 12Next-generation sequencing
- 10MicroRNAs
- 6Gene-expression
- 3Chemotherapy
- 3Positron Emission Tomography
- 30Graduate and Postdoctoral Studies (GPS), Faculty of
- 30Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 6Agricultural, Food and Nutritional Science, Department of
- 6Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Oil Sands Research and Information Network (OSRIN)
- 2Oil Sands Research and Information Network (OSRIN)/OSRIN Technical Reports
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Spring 2016
Maintenance of the gut health of calves is vital because enteric infections are associated with high mortality during the pre-weaned period. The small intestine is the primary site of many enteric infections and plays an important role in protecting the host from pathogenic infection through both...
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The role of Receptor Interacting Serine/Threonine Kinase 2 (RIPK2) in inflammatory breast cancer (IBC)
DownloadFall 2022
Inflammatory breast cancer (IBC) is a rare but aggressive type of breast cancer characterized by early and rapid metastasis leading to poor clinical outcomes. The tumor microenvironment (TME), including immune cells, fibroblasts and endothelial cells, has emerged as a major regulator of IBC...
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The Regulation of p53 by E3 ligases MDM2 and CHIP in Breast Cancer: Analysis of the Role of Hsp70 and Hsp90
DownloadSpring 2016
Tumor suppressor p53 is commonly mutated in breast cancer. Mutant p53 protein is highly stable and oncogenic. This study aims to understand the underlying mechanism of the regulation and stabilization of mutant p53 protein particularly folded mutant p53 R280K. The data showed a possible...
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Fall 2019
Breast cancer is the leading cause of death among women worldwide. Fortunately, death rates have been declining since 1990, due to the increase in early detection, testing, and improved treatment. However, despite the advancement of targeted and hormone therapies for certain molecular sub-types...
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Spring 2018
Identification of bacterial isolates is important for taxonomic purposes, as well as to predict behaviour and properties of organisms in evolutionary, ecological, industrial, or medical contexts. This process embraces a polyphasic approach (phenotypic, genotypic, and phylogenetic), but has been...
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Synthesis and Characterization of Novel Radiolabelled Substrates for Imaging of GLUT5 Expression in Human Breast Cancer Using Positron Emission Tomography
DownloadFall 2012
Overactive glucose transport and metabolism has been widely recognized as one of the fundamental hallmarks of cancer and its progression. The facilitative glucose transporter GLUT1 is widely overexpressed in many tumor types compared to their untransformed counterparts. Due to this, the glucose...
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Fall 2018
Protein kinases are critical players in cell signaling processes and their activity leads to the phosphorylation of substrates, often regulating enzymatic activity. 518 protein kinases are encoded in the human genome, however, there are many features within the catalytic domain of these proteins...
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Single-nucleotide polymorphism discovery in Leptographium longiclavatum, a mountain pine beetle-associated symbiotic fungus, using whole-genome resequencing
Download2014-01-01
Ojeda, Dario I., Dhillon, Braham, Tsui, Clement K. M., Hamelin, Richard C.
Single-nucleotide polymorphisms (SNPs) are rapidly becoming the standard markers in population genomics studies; however, their use in nonmodel organisms is limited due to the lack of cost-effective approaches to uncover genome-wide variation, and the large number of individuals needed in the...