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Skip to Search Results- 5Chan, Catherine B.
- 5Wheeler, Michael B.
- 4Guan, Leluo
- 4Koshkin, Vasilij
- 4Stothard, Paul
- 3Gänzle, Michael G.
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Whole-genome analyses of Korean native and Holstein cattle breeds by massively parallel sequencing
Download2014
Kim, Tae-Hun, Oh, Jae-Don, Han, Kwang-Jin, Choi, Jung-Woo, Choi, So-Young, Lee, Hak-Kyo, Stothard, Paul, Jeon, Heoyn-Jeong, Lee, Kyung-Tai, Lee, Jeong-Koo, Jeong, Dongkee, Kim, Namshin, Chung, Won-Hyong, Kim, Hyeong-Cheol, Liao, Xiaoping, Yang, Bokyoung, Miller, Stephen P., Lee, Sung-Jin
A main goal of cattle genomics is to identify DNA differences that account for variations in economically important traits. In this study, we performed whole-genome analyses of three important cattle breeds in Korea—Hanwoo, Jeju Heugu, and Korean Holstein—using the Illumina HiSeq 2000 sequencing...
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2015
Stothard, Paul, Wang, Yining, Lin, Guohui, Wylie, Tim
Background Despite ongoing reductions in the cost of sequencing technologies, whole genome SNP genotype imputation is often used as an alternative for obtaining abundant SNP genotypes for genome wide association studies. Several existing genotype imputation methods can be efficient for this...
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Transport and reaction processes in bioremediation of organic contaminants. 1. Review of bacterial degradation and transport
Download2003-01-01
Bressler, David C., Gray, Murray R.
Bioremediation of contaminants in soil and water involves a complex interplay between transport processes and biological reactions. Equilibrium physical factors such as aqueous solubility, soil adsorption, and phase partitioning indicate the transport processes that can limit bioremediation,...
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The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats
Download2014
Baracos, Vickie, Dieleman, Levinus, Farhangfar, Arazm, Lin, Xiaoxi B., Gänzle, Michael G., Sawyer, Michael B., Valcheva, Rosica, Schieber, Andreas
CPT-11 is a drug used as chemotherapy for colorectal cancer. CPT-11 causes toxic side-effects in patients. CPT-11 toxicity has been attributed to the activity of intestinal microbiota, however, intestinal microbiota may also have protective effects in CP!-11 chemotherapy. This study aimed to...
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The characterization of mitochondrial permeability transition (MPT) in clonal pancreatic beta cells: Multiple modes and regulation
Download2004
Chan, Catherine B., Bikopoulos, George, Koshkin, Vasilij, Wheeler, Michael B.
Mitochondrial permeability transition (MPT), which contributes substantially to the regulation of normal mitochondrial metabolism, also plays a crucial role in the initiation of cell death. It is known that MPT is regulated in a tissue-specific manner. The importance of MPT in the pancreatic...
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Taxonomic assessment of rumen microbiota using total RNA and targeted amplicon sequencing approaches
Download2016
Janssen, Peter H., Li, Fuyong, Sun, Xu, Cox, Faith, Guan, Leluo, Henderson, Gemma
Taxonomic characterization of active gastrointestinal microbiota is essential to detect shifts in microbial communities and functions under various conditions. This study aimed to identify and quantify potentially active rumen microbiota using total RNA sequencing and to compare the outcomes of...
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Rumen microbial community composition varies with diet and host, but a core microbiome is found across a wide geographical range
Download2015
Cox, Faith, Janssen, Peter H., Henderson, Gemma, Jonker, Arjan, Young, Wayne, Ganesh, Siva
Ruminant livestock are important sources of human food and global greenhouse gas emissions. Feed degradation and methane formation by ruminants rely on metabolic interactions between rumen microbes and affect ruminant productivity. Rumen and camelid foregut microbial community composition was...
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Reducing GHG emissions through genetic improvement for feed efficiency: Effects on economically important traits and enteric methane production
Download2013
Baron, Vern S., Ominski, Kim H., Guan, Leluo, Basarab, John A., Beauchemin, Karen A., Miller, Stephen P.
Genetic selection for residual feed intake (RFI) is an indirect approach for reducing enteric methane (CH4) emissions in beef and dairy cattle. RFI is moderately heritable (0.26 to 0.43), moderately repeatable across diets (0.33 to 0.67) and independent of body size and production, and when...
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Potential regulatory role of microRNAs in the development of bovine gastrointestinal tract during early life
Download2014
Liang, Guanxiang, Bao, Hua, Guan, Leluo, Griebel, Philip J., Stothard, Paul, McFadden, Thomas B., Malmuthuge, Nilusha
This study aimed to investigate the potential regulatory role of miRNAs in the development of gastrointestinal tract (GIT) during the early life of dairy calves. Rumen and small intestinal (mid-jejunum and ileum) tissue samples were collected from newborn (30 min after birth; n = 3), 7-day-old...
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Ovarian and endocrine responses associated with the treatment of cystic ovarian follicles in dairy cows with gonadotropin releasing hormone and prostaglandin F2alpha, with or without exogenous progesterone
Download2004
Schmitt, Eric J. -P., Mattos, Ricardo C., Ambrose, Divakar J., Thatcher, William W., Lopes, Flavia L.
The objectives of this observational study were to document ovarian and endocrine responses associated with the treatment of cystic ovarian follicles (COFs) in dairy cows, using gonadotropin releasing hormone (GnRH) and prostaglandin F2α(PGF) with or without exogenous progesterone. A secondary...