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Skip to Search Results- 2Al-Hallak, MHD Kamal
- 1Acton, Leah T
- 1Anwar-Mohamed, Anwar
- 1Azarmi, Shirzad
- 1Badr, Dina EFA
- 1Chen, Chao
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The biology and characterization of NOD-like receptors in goldfish (Carassius auratus L.) macrophages exposed to bacterial pathogens
DownloadSpring 2017
The recognition of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs) is important for the initiation of the host defense against pathogens. NOD-like receptors (NLRs) are a family of PRRs that primarily detect the cytosolic PAMPs of the pathogens. The NLRs have...
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Spring 2012
Development of progenitor cells into myeloid cells (i.e. macrophages and neutrophils) is critical to the survival of metazoans for maintenance of homeostasis and defense against pathogens. While much is known about myeloid cell development in mammals, less is known about this process in fish. The...
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Investigating Mechanisms Responsible for the Pro-Regenerative Effects of Conditioning Electrical Stimulation
DownloadFall 2022
Though capable of regeneration, repair surgeries following peripheral nerve injury are often incomplete or entirely unsuccessful. The slow rate of regeneration (1-3mm/day) of a proximal injury requires up to two years to reach the distal target, whereas significant muscle atrophy occurs after...
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Fall 2017
The two types of rejection identified in the Banff histopathologic diagnosis are T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR). TCMR is most common early post-transplant while ABMR is the main cause of late graft loss. Kidney transplant TCMR is diagnosed histologically...
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Inhalable nanoparticles in lung cancer treatment; efficacy, safety, distribution and nanoparticle-macrophage interactions
DownloadFall 2012
In 2002, lung cancer was responsible for 17.6% of the total worldwide deaths from cancer. Beyond the three traditional forms of cancer treatment, surgery, radiation therapy, and chemotherapy, targeted drug delivery therapy has shown to be a potential treatment option. The design of a successful...
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Examination of the Regulation of Phosphorylation Events in Macrophage Adhesion and Response to Zymosan
DownloadFall 2012
Macrophages play a central role in innate immunity, most notably in tissue repair, phagocytosis of dead or infected cells, secretion of chemokine and cytokines at sites of infection, as well as the activation of other immune cells. These roles are highly dependent on their capacity to migrate...