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- 1Autotaxin Inhibition
- 1Bacterial Pathogens
- 1Elaidic Acid
- 1Benesch, Matthew G. K.
- 1Brindley, David N.
- 1Croxen, Matthew A.
- 1Curtis, Jonathan M.
- 1Denamur, Erick
- 1Dion, Sara
Vaccenic and elaidic acid modify plasma and splenocyte membrane phospholipids and mitogen-stimulated cytokine production in obese insulin resistant JCR:LA-cp ratsDownload
This study assessed the long-term effects of dietary vaccenic acid (VA) and elaidic acid (EA) on plasma and splenocyte phospholipid (PL) composition and related changes in inflammation and splenocyte phenotypes and cytokine responses in obese/insulin resistant JCR:LA-cp rats. Relative to lean...
Small intestine early innate immunity response during intestinal colonization by Escherichia coli depends on its extra-intestinal virulence statusDownload
Uropathogenic Escherichia coli (UPEC) strains live as commensals in the digestive tract of the host, but they can also initiate urinary tract infections. The aim of this work was to determine how a host detects the presence of a new UPEC strain in the digestive tract. Mice were orally challenged...
Autotaxin (ATX) is a secreted enzyme, which produces extracellular lysophosphatidate (LPA) from lysophosphatidylcholine (LPC). LPA activates six G protein-coupled receptors and this is essential for vasculogenesis during embryonic development. ATX is also involved in wound healing and...